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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARE
All Species:
13.33
Human Site:
S417
Identified Species:
22.56
UniProt:
Q12980
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12980
NP_001070818.1
569
63605
S417
V
C
L
M
A
S
P
S
E
E
E
P
R
P
R
Chimpanzee
Pan troglodytes
XP_510703
569
63558
S417
V
C
L
M
A
S
P
S
E
E
E
P
R
P
R
Rhesus Macaque
Macaca mulatta
XP_001118432
569
63094
S417
V
C
L
M
A
S
P
S
E
E
E
P
R
P
R
Dog
Lupus familis
XP_854363
368
40934
V227
P
H
P
R
E
D
D
V
P
F
T
A
R
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIJ8
569
63599
S417
V
C
L
M
A
S
P
S
E
E
E
P
R
L
R
Rat
Rattus norvegicus
NP_001030108
469
52283
L328
K
A
V
I
I
Y
P
L
C
E
N
N
V
Y
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517960
146
16314
Chicken
Gallus gallus
XP_414946
569
63971
N417
V
C
L
M
V
P
P
N
E
E
E
F
R
A
Q
Frog
Xenopus laevis
NP_001083270
580
64646
N428
V
C
L
L
V
P
P
N
E
D
V
A
S
S
K
Zebra Danio
Brachydanio rerio
NP_001020705
596
67120
N444
V
C
L
L
V
P
P
N
E
E
E
P
G
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUB4
610
68769
M457
L
H
G
S
M
L
S
M
S
S
H
P
L
P
V
Honey Bee
Apis mellifera
XP_395986
511
58454
K370
L
P
T
S
I
S
Q
K
L
N
P
L
S
Q
S
Nematode Worm
Caenorhab. elegans
Q20069
511
57899
K370
T
L
D
T
F
I
R
K
N
L
P
L
H
E
Q
Sea Urchin
Strong. purpuratus
XP_792244
494
55249
G353
P
N
A
P
T
S
P
G
T
P
L
D
F
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
91.9
63
N.A.
96.3
77.5
N.A.
23.2
87.5
81.5
75.3
N.A.
37.3
41.4
21.4
39.8
Protein Similarity:
100
100
94.1
63.7
N.A.
98.2
79.4
N.A.
24.7
94.7
89.4
83.5
N.A.
56.3
61.3
42
57.8
P-Site Identity:
100
100
100
6.6
N.A.
93.3
13.3
N.A.
0
60
33.3
60
N.A.
13.3
6.6
0
13.3
P-Site Similarity:
100
100
100
6.6
N.A.
93.3
26.6
N.A.
0
73.3
60
73.3
N.A.
20
13.3
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
29
0
0
0
0
0
0
15
0
8
0
% A
% Cys:
0
50
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
8
0
0
8
0
8
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
50
50
43
0
0
15
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
8
0
8
8
0
8
% F
% Gly:
0
0
8
0
0
0
0
8
0
0
0
0
8
0
8
% G
% His:
0
15
0
0
0
0
0
0
0
0
8
0
8
0
0
% H
% Ile:
0
0
0
8
15
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
15
0
0
0
0
0
0
8
% K
% Leu:
15
8
50
15
0
8
0
8
8
8
8
15
8
15
0
% L
% Met:
0
0
0
36
8
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
22
8
8
8
8
0
0
0
% N
% Pro:
15
8
8
8
0
22
65
0
8
8
15
43
0
29
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
15
% Q
% Arg:
0
0
0
8
0
0
8
0
0
0
0
0
43
0
36
% R
% Ser:
0
0
0
15
0
43
8
29
8
8
0
0
15
8
8
% S
% Thr:
8
0
8
8
8
0
0
0
8
0
8
0
0
0
0
% T
% Val:
50
0
8
0
22
0
0
8
0
0
8
0
8
8
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _