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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARE
All Species:
27.88
Human Site:
S452
Identified Species:
47.18
UniProt:
Q12980
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12980
NP_001070818.1
569
63605
S452
L
S
F
G
S
P
T
S
S
D
D
M
T
L
T
Chimpanzee
Pan troglodytes
XP_510703
569
63558
S452
L
S
F
G
S
P
T
S
S
D
D
M
T
L
T
Rhesus Macaque
Macaca mulatta
XP_001118432
569
63094
S452
L
S
F
G
S
P
T
S
S
D
D
M
T
L
T
Dog
Lupus familis
XP_854363
368
40934
M262
M
T
L
T
S
P
S
M
D
N
S
S
A
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIJ8
569
63599
S452
L
S
F
G
S
P
T
S
S
D
D
M
T
L
T
Rat
Rattus norvegicus
NP_001030108
469
52283
S363
F
P
S
H
D
L
P
S
V
L
A
K
F
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517960
146
16314
G40
H
P
T
L
L
Q
H
G
L
G
Q
V
S
K
T
Chicken
Gallus gallus
XP_414946
569
63971
S452
L
S
F
G
S
P
T
S
S
D
D
M
T
L
T
Frog
Xenopus laevis
NP_001083270
580
64646
S463
L
S
F
G
S
P
T
S
S
D
D
M
T
L
T
Zebra Danio
Brachydanio rerio
NP_001020705
596
67120
S479
L
S
F
G
S
P
T
S
S
D
D
M
T
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUB4
610
68769
P492
S
D
N
I
A
V
Q
P
S
S
S
H
K
S
N
Honey Bee
Apis mellifera
XP_395986
511
58454
Y405
Q
L
H
T
Y
V
Q
Y
M
P
T
V
H
G
Q
Nematode Worm
Caenorhab. elegans
Q20069
511
57899
P405
Q
F
Y
Y
I
L
K
P
Y
S
I
A
I
L
P
Sea Urchin
Strong. purpuratus
XP_792244
494
55249
L388
L
S
D
H
R
N
R
L
A
E
R
E
R
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
91.9
63
N.A.
96.3
77.5
N.A.
23.2
87.5
81.5
75.3
N.A.
37.3
41.4
21.4
39.8
Protein Similarity:
100
100
94.1
63.7
N.A.
98.2
79.4
N.A.
24.7
94.7
89.4
83.5
N.A.
56.3
61.3
42
57.8
P-Site Identity:
100
100
100
13.3
N.A.
100
6.6
N.A.
6.6
100
100
100
N.A.
6.6
0
6.6
13.3
P-Site Similarity:
100
100
100
40
N.A.
100
6.6
N.A.
20
100
100
100
N.A.
13.3
6.6
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
0
8
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
8
0
0
0
8
50
50
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
8
0
8
8
% E
% Phe:
8
8
50
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
50
0
0
0
8
0
8
0
0
0
8
0
% G
% His:
8
0
8
15
0
0
8
0
0
0
0
8
8
0
0
% H
% Ile:
0
0
0
8
8
0
0
0
0
0
8
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
8
8
8
0
% K
% Leu:
58
8
8
8
8
15
0
8
8
8
0
0
0
58
15
% L
% Met:
8
0
0
0
0
0
0
8
8
0
0
50
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
0
0
8
0
0
0
0
8
% N
% Pro:
0
15
0
0
0
58
8
15
0
8
0
0
0
8
8
% P
% Gln:
15
0
0
0
0
8
15
0
0
0
8
0
0
0
8
% Q
% Arg:
0
0
0
0
8
0
8
0
0
0
8
0
8
0
0
% R
% Ser:
8
58
8
0
58
0
8
58
58
15
15
8
8
15
0
% S
% Thr:
0
8
8
15
0
0
50
0
0
0
8
0
50
0
58
% T
% Val:
0
0
0
0
0
15
0
0
8
0
0
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
8
0
0
8
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _