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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARE
All Species:
29.7
Human Site:
S489
Identified Species:
50.26
UniProt:
Q12980
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12980
NP_001070818.1
569
63605
S489
M
T
E
N
L
L
A
S
L
S
E
H
E
R
A
Chimpanzee
Pan troglodytes
XP_510703
569
63558
S489
M
T
E
N
L
L
A
S
L
S
E
H
E
R
A
Rhesus Macaque
Macaca mulatta
XP_001118432
569
63094
S489
M
T
E
N
L
L
A
S
L
S
E
H
E
R
A
Dog
Lupus familis
XP_854363
368
40934
S299
H
E
R
A
A
I
L
S
V
P
A
A
Q
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIJ8
569
63599
S489
M
T
E
N
L
L
A
S
L
S
E
H
E
R
A
Rat
Rattus norvegicus
NP_001030108
469
52283
R400
M
V
V
W
M
L
Q
R
R
L
L
I
Q
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517960
146
16314
S77
N
A
D
P
S
V
I
S
C
L
H
N
L
S
R
Chicken
Gallus gallus
XP_414946
569
63971
S489
M
T
E
N
L
L
A
S
L
L
E
H
E
R
E
Frog
Xenopus laevis
NP_001083270
580
64646
S500
A
T
E
N
L
L
A
S
L
S
Q
I
E
R
E
Zebra Danio
Brachydanio rerio
NP_001020705
596
67120
S516
M
T
E
T
L
L
A
S
L
T
E
H
E
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUB4
610
68769
V529
K
L
K
E
L
L
Q
V
F
S
D
A
D
R
A
Honey Bee
Apis mellifera
XP_395986
511
58454
Y442
Y
N
Y
Q
S
E
D
Y
D
I
P
S
D
D
R
Nematode Worm
Caenorhab. elegans
Q20069
511
57899
I442
V
K
G
V
V
A
D
I
C
A
E
M
L
E
T
Sea Urchin
Strong. purpuratus
XP_792244
494
55249
T425
V
F
I
I
T
N
P
T
L
A
K
K
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
91.9
63
N.A.
96.3
77.5
N.A.
23.2
87.5
81.5
75.3
N.A.
37.3
41.4
21.4
39.8
Protein Similarity:
100
100
94.1
63.7
N.A.
98.2
79.4
N.A.
24.7
94.7
89.4
83.5
N.A.
56.3
61.3
42
57.8
P-Site Identity:
100
100
100
6.6
N.A.
100
13.3
N.A.
6.6
86.6
73.3
80
N.A.
33.3
0
6.6
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
26.6
N.A.
26.6
86.6
80
86.6
N.A.
53.3
6.6
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
8
8
50
0
0
15
8
15
0
0
36
% A
% Cys:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
15
0
8
0
8
0
15
8
0
% D
% Glu:
0
8
50
8
0
8
0
0
0
0
50
0
50
8
15
% E
% Phe:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
8
43
0
0
8
% H
% Ile:
0
0
8
8
0
8
8
8
0
8
0
15
0
0
0
% I
% Lys:
8
8
8
0
0
0
0
0
0
0
8
8
0
0
0
% K
% Leu:
0
8
0
0
58
65
8
0
58
22
8
0
15
8
0
% L
% Met:
50
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
8
0
43
0
8
0
0
0
0
0
8
0
8
0
% N
% Pro:
0
0
0
8
0
0
8
0
0
8
8
0
0
0
8
% P
% Gln:
0
0
0
8
0
0
15
0
0
0
8
0
15
0
8
% Q
% Arg:
0
0
8
0
0
0
0
8
8
0
0
0
0
58
15
% R
% Ser:
0
0
0
0
15
0
0
65
0
43
0
8
8
15
8
% S
% Thr:
0
50
0
8
8
0
0
8
0
8
0
0
0
0
8
% T
% Val:
15
8
8
8
8
8
0
8
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _