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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFX1 All Species: 31.82
Human Site: S1045 Identified Species: 63.64
UniProt: Q12986 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12986 NP_002495.2 1120 124395 S1045 A Q V Y G L E S V S Y D S E P
Chimpanzee Pan troglodytes XP_001159394 1119 124447 S1044 A Q V Y G L E S V S Y D S E P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538703 1117 124116 S1042 A Q V Y G L E S V S Y D S E P
Cat Felis silvestris
Mouse Mus musculus B1AY10 1114 123793 S1039 A Q V Y G L E S I S Y D S E P
Rat Rattus norvegicus NP_001019955 1114 123953 S1039 A Q V Y G L E S V S Y D S E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418890 1214 137108 S1139 A Q V Y G I E S V S Y D N E P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_690559 1083 121080 S1007 A E V Y G V E S V S Y D N E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40798 1106 123164 K1039 F P T M N R E K R Q L V H E L
Honey Bee Apis mellifera XP_395912 1087 124598 S999 C E H F G C E S Q A Y D Q E P
Nematode Worm Caenorhab. elegans Q18034 1119 125129 T1036 E E S N V P T T S N L V S S P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172488 1188 130698 A1120 G S S T D A Q A S A L R S A K
Baker's Yeast Sacchar. cerevisiae P53971 965 108476 A898 I L D D G K T A L V Y P E N Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 92.5 N.A. 88.2 88.3 N.A. N.A. 56.9 N.A. 52.3 N.A. 34.4 36.5 36.3 N.A.
Protein Similarity: 100 99.5 N.A. 95.6 N.A. 92.3 92.4 N.A. N.A. 69.5 N.A. 65.2 N.A. 49.4 54.6 50.1 N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 100 N.A. N.A. 86.6 N.A. 80 N.A. 13.3 46.6 13.3 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 100 N.A. 100 N.A. 13.3 66.6 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.6 20 N.A.
Protein Similarity: N.A. N.A. N.A. 33 34.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 59 0 0 0 0 9 0 17 0 17 0 0 0 9 0 % A
% Cys: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 9 9 0 0 0 0 0 0 67 0 0 0 % D
% Glu: 9 25 0 0 0 0 75 0 0 0 0 0 9 75 0 % E
% Phe: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 75 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 9 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 9 0 9 0 0 0 0 0 0 9 % K
% Leu: 0 9 0 0 0 42 0 0 9 0 25 0 0 0 9 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 9 0 0 0 0 9 0 0 17 9 0 % N
% Pro: 0 9 0 0 0 9 0 0 0 0 0 9 0 0 75 % P
% Gln: 0 50 0 0 0 0 9 0 9 9 0 0 9 0 0 % Q
% Arg: 0 0 0 0 0 9 0 0 9 0 0 9 0 0 0 % R
% Ser: 0 9 17 0 0 0 0 67 17 59 0 0 59 9 0 % S
% Thr: 0 0 9 9 0 0 17 9 0 0 0 0 0 0 0 % T
% Val: 0 0 59 0 9 9 0 0 50 9 0 17 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 59 0 0 0 0 0 0 75 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _