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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFX1 All Species: 4.55
Human Site: S207 Identified Species: 9.09
UniProt: Q12986 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12986 NP_002495.2 1120 124395 S207 P E D A G P E S T K P V G V F
Chimpanzee Pan troglodytes XP_001159394 1119 124447 S206 P E D A G P E S T K P V G V F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538703 1117 124116 N206 S E D A V P E N T K P V G V I
Cat Felis silvestris
Mouse Mus musculus B1AY10 1114 123793 N201 S P K S E D E N T R P V A I S
Rat Rattus norvegicus NP_001019955 1114 123953 N201 S P K S E D E N A R P V A I S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418890 1214 137108 N286 Q K V E L F E N T P S L D L T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_690559 1083 121080 A194 G K D T K P V A V Y E H P E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40798 1106 123164 R239 N Y E R E R E R E R D R D R D
Honey Bee Apis mellifera XP_395912 1087 124598 Q194 I Q S N D I S Q S N N L I K E
Nematode Worm Caenorhab. elegans Q18034 1119 125129 E204 A R R R E Q K E E P L T E E E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172488 1188 130698 V230 C M I C Y D K V G R S A N I W
Baker's Yeast Sacchar. cerevisiae P53971 965 108476 H184 R M V E I M C H C G K H S K S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 92.5 N.A. 88.2 88.3 N.A. N.A. 56.9 N.A. 52.3 N.A. 34.4 36.5 36.3 N.A.
Protein Similarity: 100 99.5 N.A. 95.6 N.A. 92.3 92.4 N.A. N.A. 69.5 N.A. 65.2 N.A. 49.4 54.6 50.1 N.A.
P-Site Identity: 100 100 N.A. 73.3 N.A. 26.6 20 N.A. N.A. 13.3 N.A. 13.3 N.A. 6.6 0 0 N.A.
P-Site Similarity: 100 100 N.A. 80 N.A. 53.3 46.6 N.A. N.A. 40 N.A. 26.6 N.A. 20 20 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.6 20 N.A.
Protein Similarity: N.A. N.A. N.A. 33 34.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 25 0 0 0 9 9 0 0 9 17 0 0 % A
% Cys: 9 0 0 9 0 0 9 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 34 0 9 25 0 0 0 0 9 0 17 0 9 % D
% Glu: 0 25 9 17 34 0 59 9 17 0 9 0 9 17 17 % E
% Phe: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 17 % F
% Gly: 9 0 0 0 17 0 0 0 9 9 0 0 25 0 0 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 17 0 0 0 % H
% Ile: 9 0 9 0 9 9 0 0 0 0 0 0 9 25 9 % I
% Lys: 0 17 17 0 9 0 17 0 0 25 9 0 0 17 0 % K
% Leu: 0 0 0 0 9 0 0 0 0 0 9 17 0 9 0 % L
% Met: 0 17 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 9 0 0 0 34 0 9 9 0 9 0 0 % N
% Pro: 17 17 0 0 0 34 0 0 0 17 42 0 9 0 9 % P
% Gln: 9 9 0 0 0 9 0 9 0 0 0 0 0 0 0 % Q
% Arg: 9 9 9 17 0 9 0 9 0 34 0 9 0 9 0 % R
% Ser: 25 0 9 17 0 0 9 17 9 0 17 0 9 0 25 % S
% Thr: 0 0 0 9 0 0 0 0 42 0 0 9 0 0 9 % T
% Val: 0 0 17 0 9 0 9 9 9 0 0 42 0 25 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 9 0 0 9 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _