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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFX1
All Species:
8.79
Human Site:
Y231
Identified Species:
17.58
UniProt:
Q12986
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12986
NP_002495.2
1120
124395
Y231
R
K
G
V
L
D
G
Y
G
A
R
R
N
E
Q
Chimpanzee
Pan troglodytes
XP_001159394
1119
124447
Y230
R
K
G
V
L
D
G
Y
G
A
R
R
N
E
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538703
1117
124116
Y230
K
K
S
V
L
D
G
Y
G
A
R
R
N
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
B1AY10
1114
123793
C225
R
K
P
V
V
D
P
C
V
C
R
R
N
E
Q
Rat
Rattus norvegicus
NP_001019955
1114
123953
C225
R
K
P
V
V
D
P
C
V
C
R
R
S
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418890
1214
137108
P310
G
K
A
F
S
E
A
P
I
G
S
G
D
E
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690559
1083
121080
P218
G
G
E
H
R
M
Q
P
N
F
R
R
K
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40798
1106
123164
R263
D
R
D
R
D
R
D
R
D
R
D
R
D
S
R
Honey Bee
Apis mellifera
XP_395912
1087
124598
R218
Q
T
Y
N
N
H
K
R
Y
S
R
E
N
Y
Y
Nematode Worm
Caenorhab. elegans
Q18034
1119
125129
L228
R
E
G
L
V
Y
L
L
E
N
N
K
Y
E
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172488
1188
130698
W254
H
I
N
C
I
K
R
W
A
R
A
P
T
S
V
Baker's Yeast
Sacchar. cerevisiae
P53971
965
108476
E208
K
K
N
F
N
C
Q
E
V
C
G
L
P
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
92.5
N.A.
88.2
88.3
N.A.
N.A.
56.9
N.A.
52.3
N.A.
34.4
36.5
36.3
N.A.
Protein Similarity:
100
99.5
N.A.
95.6
N.A.
92.3
92.4
N.A.
N.A.
69.5
N.A.
65.2
N.A.
49.4
54.6
50.1
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
60
53.3
N.A.
N.A.
20
N.A.
13.3
N.A.
6.6
13.3
20
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
66.6
66.6
N.A.
N.A.
33.3
N.A.
13.3
N.A.
26.6
26.6
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.6
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33
34.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
9
0
9
25
9
0
0
0
0
% A
% Cys:
0
0
0
9
0
9
0
17
0
25
0
0
0
0
9
% C
% Asp:
9
0
9
0
9
42
9
0
9
0
9
0
17
0
0
% D
% Glu:
0
9
9
0
0
9
0
9
9
0
0
9
0
59
0
% E
% Phe:
0
0
0
17
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
17
9
25
0
0
0
25
0
25
9
9
9
0
9
0
% G
% His:
9
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
9
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
17
59
0
0
0
9
9
0
0
0
0
9
9
0
0
% K
% Leu:
0
0
0
9
25
0
9
9
0
0
0
9
0
9
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
17
9
17
0
0
0
9
9
9
0
42
0
0
% N
% Pro:
0
0
17
0
0
0
17
17
0
0
0
9
9
0
9
% P
% Gln:
9
0
0
0
0
0
17
0
0
0
0
0
0
0
50
% Q
% Arg:
42
9
0
9
9
9
9
17
0
17
59
59
0
0
9
% R
% Ser:
0
0
9
0
9
0
0
0
0
9
9
0
9
17
9
% S
% Thr:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% T
% Val:
0
0
0
42
25
0
0
0
25
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
9
0
25
9
0
0
0
9
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _