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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPB3
All Species:
22.73
Human Site:
Y16
Identified Species:
50
UniProt:
Q12988
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12988
NP_006299.1
150
16966
Y16
L
I
E
I
P
V
R
Y
Q
E
E
F
E
A
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096576
150
17010
Y16
L
I
E
I
P
V
R
Y
Q
E
E
F
E
T
R
Dog
Lupus familis
XP_536473
150
16975
Y16
L
I
E
T
P
V
R
Y
E
E
E
F
E
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ57
154
17211
Y16
L
I
E
T
P
V
R
Y
Q
E
E
F
E
A
R
Rat
Rattus norvegicus
Q9QZ58
152
17191
Y16
L
I
E
T
P
V
R
Y
Q
E
E
F
E
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521038
157
17557
Y16
P
I
E
T
P
V
R
Y
Q
G
H
F
A
T
R
Chicken
Gallus gallus
Q00649
193
21653
P39
S
F
G
M
P
H
I
P
E
D
W
Y
K
W
P
Frog
Xenopus laevis
NP_001087285
213
23719
D21
P
S
W
D
P
F
R
D
W
Y
Q
G
S
S
R
Zebra Danio
Brachydanio rerio
NP_001092922
150
17096
Y18
W
I
S
S
P
V
R
Y
Q
Q
L
F
K
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02516
186
20611
L10
N
I
P
L
L
L
S
L
A
D
D
L
G
R
M
Honey Bee
Apis mellifera
XP_394333
191
21957
F8
M
S
V
V
P
L
I
F
R
D
W
W
D
D
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96
90
N.A.
85.7
87.5
N.A.
64.9
26.9
28.6
52.6
N.A.
28.4
29.8
N.A.
N.A.
Protein Similarity:
100
N.A.
96.6
93.3
N.A.
88.3
89.4
N.A.
72.6
42.4
42.7
65.3
N.A.
42.4
45
N.A.
N.A.
P-Site Identity:
100
N.A.
93.3
86.6
N.A.
93.3
93.3
N.A.
60
6.6
20
53.3
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
60
40
33.3
66.6
N.A.
33.3
60
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
10
37
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
10
0
28
10
0
10
10
0
% D
% Glu:
0
0
55
0
0
0
0
0
19
46
46
0
46
0
0
% E
% Phe:
0
10
0
0
0
10
0
10
0
0
0
64
0
0
10
% F
% Gly:
0
0
10
0
0
0
0
0
0
10
0
10
10
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
73
0
19
0
0
19
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% K
% Leu:
46
0
0
10
10
19
0
10
0
0
10
10
0
0
0
% L
% Met:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
19
0
10
0
91
0
0
10
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
55
10
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
73
0
10
0
0
0
0
10
73
% R
% Ser:
10
19
10
10
0
0
10
0
0
0
0
0
10
10
0
% S
% Thr:
0
0
0
37
0
0
0
0
0
0
0
0
0
28
0
% T
% Val:
0
0
10
10
0
64
0
0
0
0
0
0
0
0
0
% V
% Trp:
10
0
10
0
0
0
0
0
10
0
19
10
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
64
0
10
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _