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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSTF3 All Species: 34.24
Human Site: S117 Identified Species: 57.95
UniProt: Q12996 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12996 NP_001317.1 717 82922 S117 E T K G K L P S Y K E K M A Q
Chimpanzee Pan troglodytes XP_001143931 749 86255 S149 E T K G K L P S Y K E K M A Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533159 717 82899 S117 E T K G K L P S Y K E K M A Q
Cat Felis silvestris
Mouse Mus musculus Q99LI7 717 82858 S117 E T K G K L P S Y K E K M A Q
Rat Rattus norvegicus NP_001071140 590 69247 K52 Q P I D K A R K T Y E R L V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507079 820 94279 S220 E T K G K L P S Y K E K M A Q
Chicken Gallus gallus NP_001012586 718 83053 S118 E T K G K L P S Y K E K M A Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998218 716 82797 S117 E T K G K L P S Y K E K M P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25991 765 88196 T118 E T K S G L S T H K E K M A Q
Honey Bee Apis mellifera XP_393870 713 82097 T114 E T K A S L T T Y K E K M A Q
Nematode Worm Caenorhab. elegans NP_495825 735 84603 Q105 E T K G Q R D Q Y R E E M A K
Sea Urchin Strong. purpuratus XP_796577 557 65419 P19 E N G W G Y V P E K V K K A Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P25298 677 79942 D120 S L W S T Y L D Y I R R K N N
Red Bread Mold Neurospora crassa Q7S1Y0 1167 128472 Q352 D L N D S T G Q A R Q T V S Q
Conservation
Percent
Protein Identity: 100 95.7 N.A. 99.8 N.A. 99.3 78.5 N.A. 85.9 98 N.A. 90.7 N.A. 53.5 62.6 48.7 56.9
Protein Similarity: 100 95.7 N.A. 99.8 N.A. 99.5 79.9 N.A. 86.7 99.3 N.A. 95.4 N.A. 71.6 78.2 68.4 67.2
P-Site Identity: 100 100 N.A. 100 N.A. 100 13.3 N.A. 100 100 N.A. 93.3 N.A. 66.6 73.3 53.3 33.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 33.3 N.A. 100 100 N.A. 93.3 N.A. 80 80 80 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 21.6
Protein Similarity: N.A. N.A. N.A. N.A. 46.7 35.3
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 8 0 0 8 0 0 0 0 72 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 15 0 0 8 8 0 0 0 0 0 0 0 % D
% Glu: 79 0 0 0 0 0 0 0 8 0 79 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 58 15 0 8 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 72 0 58 0 0 8 0 72 0 72 15 0 8 % K
% Leu: 0 15 0 0 0 65 8 0 0 0 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 72 0 0 % M
% Asn: 0 8 8 0 0 0 0 0 0 0 0 0 0 8 8 % N
% Pro: 0 8 0 0 0 0 50 8 0 0 0 0 0 8 0 % P
% Gln: 8 0 0 0 8 0 0 15 0 0 8 0 0 0 79 % Q
% Arg: 0 0 0 0 0 8 8 0 0 15 8 15 0 0 0 % R
% Ser: 8 0 0 15 15 0 8 50 0 0 0 0 0 8 0 % S
% Thr: 0 72 0 0 8 8 8 15 8 0 0 8 0 0 0 % T
% Val: 0 0 0 0 0 0 8 0 0 0 8 0 8 8 0 % V
% Trp: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 15 0 0 72 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _