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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSTF3 All Species: 22.73
Human Site: S566 Identified Species: 38.46
UniProt: Q12996 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12996 NP_001317.1 717 82922 S566 P D P V V A P S I V P V L K D
Chimpanzee Pan troglodytes XP_001143931 749 86255 S598 P D P V V A P S I V P V L K D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533159 717 82899 S566 P D P V V A P S I V P V L K D
Cat Felis silvestris
Mouse Mus musculus Q99LI7 717 82858 S566 P D P V V A P S I V P V L K D
Rat Rattus norvegicus NP_001071140 590 69247 N494 R F L A F E S N I G D L A S I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507079 820 94279 S669 P D P V V A P S I V P V L K D
Chicken Gallus gallus NP_001012586 718 83053 S567 P D P V V A P S I V P V L K D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998218 716 82797 P565 I P E A V V A P S T P A L K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25991 765 88196 Q599 V G G G A Q S Q N T G E V E T
Honey Bee Apis mellifera XP_393870 713 82097 L572 P E E A I A S L P R P D I S Q
Nematode Worm Caenorhab. elegans NP_495825 735 84603 I568 G P Q A A S A I M G G A G G H
Sea Urchin Strong. purpuratus XP_796577 557 65419 L461 Y V D Y L S H L N E D N N T R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P25298 677 79942 N569 R Y Q I Q N S N L I K K L E L
Red Bread Mold Neurospora crassa Q7S1Y0 1167 128472 R1012 S H R L N P S R M V S L L Q N
Conservation
Percent
Protein Identity: 100 95.7 N.A. 99.8 N.A. 99.3 78.5 N.A. 85.9 98 N.A. 90.7 N.A. 53.5 62.6 48.7 56.9
Protein Similarity: 100 95.7 N.A. 99.8 N.A. 99.5 79.9 N.A. 86.7 99.3 N.A. 95.4 N.A. 71.6 78.2 68.4 67.2
P-Site Identity: 100 100 N.A. 100 N.A. 100 6.6 N.A. 100 100 N.A. 33.3 N.A. 0 20 0 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 20 N.A. 100 100 N.A. 33.3 N.A. 13.3 40 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 21.6
Protein Similarity: N.A. N.A. N.A. N.A. 46.7 35.3
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 40 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 29 15 50 15 0 0 0 0 15 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 43 8 0 0 0 0 0 0 0 15 8 0 0 50 % D
% Glu: 0 8 15 0 0 8 0 0 0 8 0 8 0 15 0 % E
% Phe: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 8 8 8 0 0 0 0 0 15 15 0 8 8 0 % G
% His: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 8 % H
% Ile: 8 0 0 8 8 0 0 8 50 8 0 0 8 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 8 8 0 50 0 % K
% Leu: 0 0 8 8 8 0 0 15 8 0 0 15 65 0 8 % L
% Met: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 8 0 15 15 0 0 8 8 0 8 % N
% Pro: 50 15 43 0 0 8 43 8 8 0 58 0 0 0 0 % P
% Gln: 0 0 15 0 8 8 0 8 0 0 0 0 0 8 8 % Q
% Arg: 15 0 8 0 0 0 0 8 0 8 0 0 0 0 8 % R
% Ser: 8 0 0 0 0 15 36 43 8 0 8 0 0 15 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 15 0 0 0 8 8 % T
% Val: 8 8 0 43 50 8 0 0 0 50 0 43 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _