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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSTF3
All Species:
31.82
Human Site:
T273
Identified Species:
53.85
UniProt:
Q12996
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12996
NP_001317.1
717
82922
T273
T
E
D
Q
T
L
I
T
K
R
V
M
F
A
Y
Chimpanzee
Pan troglodytes
XP_001143931
749
86255
T305
T
E
D
Q
T
L
I
T
K
R
V
M
F
A
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533159
717
82899
T273
T
E
D
Q
T
L
I
T
K
R
V
M
F
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q99LI7
717
82858
T273
T
E
D
Q
T
L
I
T
K
R
V
M
F
A
Y
Rat
Rattus norvegicus
NP_001071140
590
69247
K203
G
I
N
I
H
L
A
K
K
M
I
E
D
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507079
820
94279
T376
T
E
D
Q
T
L
I
T
K
R
V
M
F
A
Y
Chicken
Gallus gallus
NP_001012586
718
83053
T274
T
E
D
Q
T
L
I
T
K
R
V
M
F
A
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998218
716
82797
T273
T
E
D
Q
T
L
I
T
K
R
V
M
F
A
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25991
765
88196
T274
T
E
D
T
A
L
V
T
R
R
V
M
F
A
T
Honey Bee
Apis mellifera
XP_393870
713
82097
A270
T
E
D
T
S
L
V
A
R
R
V
M
F
A
I
Nematode Worm
Caenorhab. elegans
NP_495825
735
84603
A261
T
E
E
Y
G
Q
H
A
R
R
V
V
Y
T
Y
Sea Urchin
Strong. purpuratus
XP_796577
557
65419
T170
Y
A
E
N
Q
R
I
T
A
V
R
R
V
F
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25298
677
79942
Q275
G
T
S
D
S
N
I
Q
Q
L
Q
I
W
L
N
Red Bread Mold
Neurospora crassa
Q7S1Y0
1167
128472
D511
S
D
P
L
D
L
K
D
D
K
D
Q
P
G
L
Conservation
Percent
Protein Identity:
100
95.7
N.A.
99.8
N.A.
99.3
78.5
N.A.
85.9
98
N.A.
90.7
N.A.
53.5
62.6
48.7
56.9
Protein Similarity:
100
95.7
N.A.
99.8
N.A.
99.5
79.9
N.A.
86.7
99.3
N.A.
95.4
N.A.
71.6
78.2
68.4
67.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
100
100
N.A.
100
N.A.
66.6
60
33.3
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
26.6
N.A.
100
100
N.A.
100
N.A.
80
80
60
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
21.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.7
35.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
8
15
8
0
0
0
0
65
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
65
8
8
0
0
8
8
0
8
0
8
0
0
% D
% Glu:
0
72
15
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
65
8
0
% F
% Gly:
15
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
0
0
65
0
0
0
8
8
0
0
8
% I
% Lys:
0
0
0
0
0
0
8
8
58
8
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
79
0
0
0
8
0
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
65
0
0
0
% M
% Asn:
0
0
8
8
0
8
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
50
8
8
0
8
8
0
8
8
0
0
8
% Q
% Arg:
0
0
0
0
0
8
0
0
22
72
8
8
0
8
0
% R
% Ser:
8
0
8
0
15
0
0
0
0
0
0
0
0
0
8
% S
% Thr:
72
8
0
15
50
0
0
65
0
0
0
0
0
8
8
% T
% Val:
0
0
0
0
0
0
15
0
0
8
72
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
8
0
0
8
0
0
0
0
0
0
0
0
8
0
58
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _