KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSTF3
All Species:
27.58
Human Site:
T586
Identified Species:
46.67
UniProt:
Q12996
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12996
NP_001317.1
717
82922
T586
P
E
Y
P
K
P
D
T
Q
Q
M
I
P
F
Q
Chimpanzee
Pan troglodytes
XP_001143931
749
86255
T618
P
E
Y
P
K
P
D
T
Q
Q
M
I
P
F
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533159
717
82899
T586
P
E
Y
P
K
P
D
T
Q
Q
M
I
P
F
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q99LI7
717
82858
T586
P
E
Y
P
K
P
D
T
Q
Q
M
I
P
F
Q
Rat
Rattus norvegicus
NP_001071140
590
69247
E514
R
R
F
T
A
F
R
E
E
Y
E
G
K
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507079
820
94279
T689
P
E
Y
P
K
P
D
T
Q
Q
M
I
P
F
Q
Chicken
Gallus gallus
NP_001012586
718
83053
T587
P
E
Y
P
K
P
D
T
Q
Q
M
I
P
F
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998218
716
82797
T585
P
E
Y
P
K
P
D
T
C
Q
M
I
P
F
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25991
765
88196
F619
P
P
L
P
R
P
D
F
S
Q
M
I
P
F
K
Honey Bee
Apis mellifera
XP_393870
713
82097
G592
P
K
V
N
P
L
P
G
E
H
P
V
P
G
G
Nematode Worm
Caenorhab. elegans
NP_495825
735
84603
I588
Y
G
F
P
R
P
D
I
S
Q
M
I
P
F
K
Sea Urchin
Strong. purpuratus
XP_796577
557
65419
P481
V
L
T
S
G
S
L
P
Q
E
Q
S
G
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25298
677
79942
S589
E
E
E
D
S
Y
F
S
S
G
N
G
D
G
H
Red Bread Mold
Neurospora crassa
Q7S1Y0
1167
128472
R1032
Y
L
D
W
K
R
E
R
E
R
M
Q
Q
M
Q
Conservation
Percent
Protein Identity:
100
95.7
N.A.
99.8
N.A.
99.3
78.5
N.A.
85.9
98
N.A.
90.7
N.A.
53.5
62.6
48.7
56.9
Protein Similarity:
100
95.7
N.A.
99.8
N.A.
99.5
79.9
N.A.
86.7
99.3
N.A.
95.4
N.A.
71.6
78.2
68.4
67.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
100
100
N.A.
93.3
N.A.
60
13.3
53.3
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
100
100
N.A.
93.3
N.A.
73.3
33.3
73.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
21.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.7
35.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
65
0
0
0
0
0
8
0
0
% D
% Glu:
8
58
8
0
0
0
8
8
22
8
8
0
0
15
0
% E
% Phe:
0
0
15
0
0
8
8
8
0
0
0
0
0
65
0
% F
% Gly:
0
8
0
0
8
0
0
8
0
8
0
15
8
15
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
65
0
0
0
% I
% Lys:
0
8
0
0
58
0
0
0
0
0
0
0
8
0
15
% K
% Leu:
0
15
8
0
0
8
8
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
72
0
0
8
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
65
8
0
65
8
65
8
8
0
0
8
0
72
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
50
65
8
8
8
0
58
% Q
% Arg:
8
8
0
0
15
8
8
8
0
8
0
0
0
0
0
% R
% Ser:
0
0
0
8
8
8
0
8
22
0
0
8
0
0
0
% S
% Thr:
0
0
8
8
0
0
0
50
0
0
0
0
0
0
15
% T
% Val:
8
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
50
0
0
8
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _