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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIAM1
All Species:
20
Human Site:
S172
Identified Species:
73.33
UniProt:
Q13009
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13009
NP_003244.2
1591
177508
S172
F
K
K
K
R
S
K
S
A
D
I
W
R
E
D
Chimpanzee
Pan troglodytes
XP_001162796
1591
177528
S172
F
K
K
K
R
S
K
S
A
D
I
W
R
E
D
Rhesus Macaque
Macaca mulatta
XP_001098107
1591
177452
S172
F
K
K
K
R
S
K
S
A
D
I
W
R
E
D
Dog
Lupus familis
XP_544855
1591
177339
S172
F
K
K
K
R
S
K
S
A
D
I
W
R
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q60610
1591
177515
S172
F
K
K
K
R
S
K
S
A
D
I
W
R
E
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91620
2061
229913
Y340
P
H
K
E
R
Y
Q
Y
V
P
K
T
K
E
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788791
1150
129570
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.4
95.7
N.A.
95.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
27.5
N.A.
N.A.
25.4
Protein Similarity:
100
99.8
99.6
97.8
N.A.
97.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
42.9
N.A.
N.A.
40.7
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
72
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
72
0
0
0
0
72
% D
% Glu:
0
0
0
15
0
0
0
0
0
0
0
0
0
86
0
% E
% Phe:
72
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
72
0
0
0
0
% I
% Lys:
0
72
86
72
0
0
72
0
0
0
15
0
15
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
15
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
86
0
0
0
0
0
0
0
72
0
0
% R
% Ser:
0
0
0
0
0
72
0
72
0
0
0
0
0
0
15
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
72
0
0
0
% W
% Tyr:
0
0
0
0
0
15
0
15
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _