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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC16 All Species: 42.12
Human Site: S131 Identified Species: 61.78
UniProt: Q13042 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13042 NP_001072113.1 620 71656 S131 S Q S S I K S S I C L L R G K
Chimpanzee Pan troglodytes XP_001141335 657 75449 S168 S Q S S I K S S I C L L R G K
Rhesus Macaque Macaca mulatta XP_001089625 620 71585 S131 S Q S S I K S S I C L L R G K
Dog Lupus familis XP_848577 620 71476 S131 S Q S S I K S S I C L L R G K
Cat Felis silvestris
Mouse Mus musculus Q8R349 620 71442 S131 S Q S S I K S S I C L L R G K
Rat Rattus norvegicus NP_001019915 620 71343 S131 S Q S S I K S S I C L L R G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513048 324 37070
Chicken Gallus gallus NP_001006265 624 72618 S131 S Q S S I K S S I C L L R G K
Frog Xenopus laevis NP_001087093 621 71792 S129 S Q S S I K S S I C L L R G K
Zebra Danio Brachydanio rerio NP_001032466 616 70436 S131 S P S S I N S S I C L L R G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623316 640 73022 S133 A P K N V Q S S I L Y V K G R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203133 551 62760 P89 K D E L D R I P L Q N V E S S
Poplar Tree Populus trichocarpa XP_002331799 542 62607 A79 L R F R Y L A A K C L E E L K
Maize Zea mays NP_001141501 580 66070 L116 R D L R F R F L A A K C L E E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_565188 543 61743 A79 L R F R Y L A A K C L E E L K
Baker's Yeast Sacchar. cerevisiae P09798 840 94974 S360 G G I K M E S S L C F L R G K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 99.3 97.9 N.A. 95.4 95.9 N.A. 48.2 91.5 88.8 79.1 N.A. N.A. 49.6 N.A. 49
Protein Similarity: 100 94.3 99.6 98.5 N.A. 97.9 98 N.A. 50.1 95.8 95.8 87.9 N.A. N.A. 68.1 N.A. 66.7
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 100 100 86.6 N.A. N.A. 26.6 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 0 100 100 86.6 N.A. N.A. 73.3 N.A. 20
Percent
Protein Identity: 35.8 36.9 N.A. 38.2 23.8 N.A.
Protein Similarity: 52.1 54.6 N.A. 54.3 41.5 N.A.
P-Site Identity: 20 0 N.A. 20 46.6 N.A.
P-Site Similarity: 40 13.3 N.A. 40 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 0 13 13 7 7 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 75 0 7 0 0 0 % C
% Asp: 0 13 0 0 7 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 7 0 0 7 0 0 0 0 0 13 19 7 7 % E
% Phe: 0 0 13 0 7 0 7 0 0 0 7 0 0 0 0 % F
% Gly: 7 7 0 0 0 0 0 0 0 0 0 0 0 69 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 57 0 7 0 63 0 0 0 0 0 0 % I
% Lys: 7 0 7 7 0 50 0 0 13 0 7 0 7 0 75 % K
% Leu: 13 0 7 7 0 13 0 7 13 7 69 63 7 13 0 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 7 0 0 0 0 7 0 0 0 0 % N
% Pro: 0 13 0 0 0 0 0 7 0 0 0 0 0 0 0 % P
% Gln: 0 50 0 0 0 7 0 0 0 7 0 0 0 0 0 % Q
% Arg: 7 13 0 19 0 13 0 0 0 0 0 0 63 0 7 % R
% Ser: 57 0 57 57 0 0 69 69 0 0 0 0 0 7 7 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 7 0 0 0 0 0 0 13 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 13 0 0 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _