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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STK4
All Species:
24.55
Human Site:
S422
Identified Species:
41.54
UniProt:
Q13043
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13043
NP_006273.1
487
55630
S422
V
P
G
P
L
K
N
S
S
D
W
K
I
P
Q
Chimpanzee
Pan troglodytes
XP_001153224
503
57116
S438
V
P
G
P
L
K
N
S
S
D
W
K
I
P
Q
Rhesus Macaque
Macaca mulatta
A4K2T0
487
55587
S422
V
P
G
P
L
K
N
S
S
D
W
K
I
P
Q
Dog
Lupus familis
XP_534432
487
55507
S422
V
P
G
P
L
R
N
S
S
D
W
K
V
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI11
487
55523
S422
V
S
G
S
L
K
N
S
S
D
W
K
I
P
Q
Rat
Rattus norvegicus
O54748
491
56103
C418
D
Q
S
M
R
E
P
C
P
M
S
N
N
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518508
281
31761
H239
T
A
T
Q
L
L
Q
H
P
F
V
K
G
A
K
Chicken
Gallus gallus
Q5ZJK4
486
55318
S421
V
S
G
Q
T
K
N
S
S
D
W
K
V
P
Q
Frog
Xenopus laevis
Q6PA14
485
55246
E422
P
T
S
T
D
P
S
E
W
K
I
P
L
N
G
Zebra Danio
Brachydanio rerio
Q7ZUQ3
492
56062
P418
F
N
H
N
Q
Q
D
P
C
L
I
S
K
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T0S6
669
75091
S484
K
P
I
A
T
E
Y
S
P
A
A
A
E
Q
Q
Honey Bee
Apis mellifera
XP_393691
465
52970
F413
F
T
E
R
D
F
D
F
L
K
F
L
S
Y
E
Nematode Worm
Caenorhab. elegans
Q9NB31
497
55620
N435
N
T
E
A
E
Y
E
N
R
F
Q
R
A
V
V
Sea Urchin
Strong. purpuratus
XP_781787
488
55060
S423
V
T
P
P
I
N
P
S
N
A
P
T
V
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
99.3
97.3
N.A.
97.3
78
N.A.
55.8
92.1
76.5
77
N.A.
45.4
62.4
52.3
64.9
Protein Similarity:
100
95.8
99.7
98.9
N.A.
98.5
89.6
N.A.
57.2
96.5
86.8
87.4
N.A.
58.5
77.8
68.4
79.1
P-Site Identity:
100
100
100
86.6
N.A.
86.6
0
N.A.
13.3
73.3
0
0
N.A.
20
0
0
26.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
6.6
N.A.
20
80
13.3
13.3
N.A.
26.6
20
13.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
15
0
0
0
0
0
15
8
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
15
0
15
0
0
43
0
0
0
0
0
% D
% Glu:
0
0
15
0
8
15
8
8
0
0
0
0
8
0
8
% E
% Phe:
15
0
0
0
0
8
0
8
0
15
8
0
0
0
8
% F
% Gly:
0
0
43
0
0
0
0
0
0
0
0
0
8
0
8
% G
% His:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
0
0
0
15
0
29
0
0
% I
% Lys:
8
0
0
0
0
36
0
0
0
15
0
50
8
0
8
% K
% Leu:
0
0
0
0
43
8
0
0
8
8
0
8
8
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
8
0
8
0
8
43
8
8
0
0
8
8
8
0
% N
% Pro:
8
36
8
36
0
8
15
8
22
0
8
8
0
50
0
% P
% Gln:
0
8
0
15
8
8
8
0
0
0
8
0
0
8
50
% Q
% Arg:
0
0
0
8
8
8
0
0
8
0
0
8
0
0
0
% R
% Ser:
0
15
15
8
0
0
8
58
43
0
8
8
8
0
8
% S
% Thr:
8
29
8
8
15
0
0
0
0
0
0
8
0
8
0
% T
% Val:
50
0
0
0
0
0
0
0
0
0
8
0
22
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
43
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _