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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STK4
All Species:
29.39
Human Site:
T353
Identified Species:
49.74
UniProt:
Q13043
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13043
NP_006273.1
487
55630
T353
T
M
T
D
G
A
N
T
M
I
E
H
D
D
T
Chimpanzee
Pan troglodytes
XP_001153224
503
57116
T369
T
M
T
D
G
A
N
T
M
I
E
H
D
D
T
Rhesus Macaque
Macaca mulatta
A4K2T0
487
55587
T353
T
M
T
D
G
A
S
T
M
I
E
H
D
D
T
Dog
Lupus familis
XP_534432
487
55507
T353
T
T
S
D
G
A
S
T
M
I
E
H
G
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI11
487
55523
T353
T
M
S
G
G
A
N
T
M
I
E
H
G
D
T
Rat
Rattus norvegicus
O54748
491
56103
T349
T
M
S
E
G
A
Q
T
M
I
E
H
N
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518508
281
31761
S170
N
C
V
A
D
I
W
S
L
G
I
T
A
I
E
Chicken
Gallus gallus
Q5ZJK4
486
55318
T352
T
M
S
D
G
A
N
T
M
I
E
H
D
G
T
Frog
Xenopus laevis
Q6PA14
485
55246
G353
M
M
S
E
G
A
D
G
T
M
V
E
K
D
K
Zebra Danio
Brachydanio rerio
Q7ZUQ3
492
56062
T349
T
M
S
D
G
A
Q
T
M
I
E
H
G
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T0S6
669
75091
P415
A
A
S
P
L
D
M
P
A
V
D
S
G
T
M
Honey Bee
Apis mellifera
XP_393691
465
52970
L344
T
L
V
P
S
H
D
L
P
D
T
G
T
L
V
Nematode Worm
Caenorhab. elegans
Q9NB31
497
55620
P366
L
R
I
G
G
E
I
P
K
S
A
Y
I
P
G
Sea Urchin
Strong. purpuratus
XP_781787
488
55060
H354
T
A
N
T
F
I
E
H
D
D
V
T
D
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
99.3
97.3
N.A.
97.3
78
N.A.
55.8
92.1
76.5
77
N.A.
45.4
62.4
52.3
64.9
Protein Similarity:
100
95.8
99.7
98.9
N.A.
98.5
89.6
N.A.
57.2
96.5
86.8
87.4
N.A.
58.5
77.8
68.4
79.1
P-Site Identity:
100
100
93.3
73.3
N.A.
80
66.6
N.A.
0
86.6
26.6
73.3
N.A.
0
6.6
6.6
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
13.3
93.3
53.3
80
N.A.
20
20
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
0
8
0
65
0
0
8
0
8
0
8
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
43
8
8
15
0
8
15
8
0
36
43
8
% D
% Glu:
0
0
0
15
0
8
8
0
0
0
58
8
0
0
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
15
72
0
0
8
0
8
0
8
29
8
8
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
58
0
0
0
% H
% Ile:
0
0
8
0
0
15
8
0
0
58
8
0
8
15
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
8
% K
% Leu:
8
8
0
0
8
0
0
8
8
0
0
0
0
8
0
% L
% Met:
8
58
0
0
0
0
8
0
58
8
0
0
0
0
8
% M
% Asn:
8
0
8
0
0
0
29
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
15
0
0
0
15
8
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
50
0
8
0
15
8
0
8
0
8
0
15
0
% S
% Thr:
72
8
22
8
0
0
0
58
8
0
8
15
8
8
58
% T
% Val:
0
0
15
0
0
0
0
0
0
8
15
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _