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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FLII All Species: 35.15
Human Site: S159 Identified Species: 70.3
UniProt: Q13045 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13045 NP_002009.1 1269 144751 S159 D L L Y L D L S E N R L E S L
Chimpanzee Pan troglodytes XP_511321 1458 164815 S346 D L L Y L D L S E N R L E S L
Rhesus Macaque Macaca mulatta XP_001094628 1256 143248 S159 D L L Y L D L S E N R L E S L
Dog Lupus familis XP_536659 1147 130372 R156 Y L D L S E N R L E S L P P Q
Cat Felis silvestris
Mouse Mus musculus Q9JJ28 1271 144785 S159 D L L Y L D L S E N R L E S L
Rat Rattus norvegicus NP_001008280 1270 144839 S159 D L L Y L D L S E N R L E S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001025806 1265 144848 S159 D L L Y L D L S N N K L E S L
Frog Xenopus laevis NP_001086319 1270 145779 S159 D L L Y L D V S D N K L D S L
Zebra Danio Brachydanio rerio XP_688770 1259 143734 S159 D L L Y L D L S D N N L D S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24020 1256 143664 E160 D L S H N R L E T L P P Q T R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34268 1257 144797 S158 D L L F L D L S N N K L D M L
Sea Urchin Strong. purpuratus XP_790260 1140 130867 L156 I F N N N P L L H S Q L R Q L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.3 97.2 86.8 N.A. 95.1 95.1 N.A. N.A. 87.7 82.8 83.6 N.A. 57.2 N.A. 51.1 50.5
Protein Similarity: 100 84.5 98.1 88 N.A. 96.8 96.7 N.A. N.A. 93.3 91.8 91.4 N.A. 74.1 N.A. 69.9 67.9
P-Site Identity: 100 100 100 13.3 N.A. 100 100 N.A. N.A. 86.6 73.3 80 N.A. 20 N.A. 66.6 20
P-Site Similarity: 100 100 100 20 N.A. 100 100 N.A. N.A. 93.3 100 93.3 N.A. 40 N.A. 86.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 84 0 9 0 0 75 0 0 17 0 0 0 25 0 0 % D
% Glu: 0 0 0 0 0 9 0 9 42 9 0 0 50 0 0 % E
% Phe: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 25 0 0 0 0 % K
% Leu: 0 92 75 9 75 0 84 9 9 9 0 92 0 0 84 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 9 9 17 0 9 0 17 75 9 0 0 0 0 % N
% Pro: 0 0 0 0 0 9 0 0 0 0 9 9 9 9 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 0 9 9 9 % Q
% Arg: 0 0 0 0 0 9 0 9 0 0 42 0 9 0 9 % R
% Ser: 0 0 9 0 9 0 0 75 0 9 9 0 0 67 0 % S
% Thr: 0 0 0 0 0 0 0 0 9 0 0 0 0 9 0 % T
% Val: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 67 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _