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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FLII
All Species:
26.06
Human Site:
S247
Identified Species:
52.12
UniProt:
Q13045
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13045
NP_002009.1
1269
144751
S247
E
C
L
Y
T
L
P
S
L
R
R
L
N
L
S
Chimpanzee
Pan troglodytes
XP_511321
1458
164815
S470
E
C
L
Y
T
L
P
S
L
R
R
L
N
L
S
Rhesus Macaque
Macaca mulatta
XP_001094628
1256
143248
S247
E
C
L
Y
T
L
P
S
L
R
R
L
N
L
S
Dog
Lupus familis
XP_536659
1147
130372
S241
E
C
L
Y
T
L
P
S
L
R
R
L
N
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJ28
1271
144785
S247
E
C
L
Y
T
L
P
S
L
R
R
L
N
L
S
Rat
Rattus norvegicus
NP_001008280
1270
144839
N247
E
C
L
Y
T
L
P
N
L
H
R
L
N
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025806
1265
144848
S247
E
C
L
Y
T
L
G
S
L
R
R
L
N
L
S
Frog
Xenopus laevis
NP_001086319
1270
145779
N247
E
C
L
Y
T
L
S
N
L
K
R
L
N
L
S
Zebra Danio
Brachydanio rerio
XP_688770
1259
143734
N247
E
C
L
Y
S
L
V
N
L
K
R
L
N
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24020
1256
143664
T243
D
C
V
Y
N
V
V
T
L
V
R
L
N
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34268
1257
144797
N246
E
A
L
F
K
L
R
N
L
R
K
L
N
L
S
Sea Urchin
Strong. purpuratus
XP_790260
1140
130867
K239
A
I
A
P
T
L
C
K
L
I
S
L
K
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.3
97.2
86.8
N.A.
95.1
95.1
N.A.
N.A.
87.7
82.8
83.6
N.A.
57.2
N.A.
51.1
50.5
Protein Similarity:
100
84.5
98.1
88
N.A.
96.8
96.7
N.A.
N.A.
93.3
91.8
91.4
N.A.
74.1
N.A.
69.9
67.9
P-Site Identity:
100
100
100
100
N.A.
100
86.6
N.A.
N.A.
93.3
80
73.3
N.A.
53.3
N.A.
60
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
93.3
93.3
93.3
N.A.
80
N.A.
80
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
84
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
84
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
9
0
0
9
0
17
9
0
9
0
0
% K
% Leu:
0
0
84
0
0
92
0
0
100
0
0
100
0
92
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
34
0
0
0
0
92
0
0
% N
% Pro:
0
0
0
9
0
0
50
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
0
0
59
84
0
0
9
0
% R
% Ser:
0
0
0
0
9
0
9
50
0
0
9
0
0
0
92
% S
% Thr:
0
0
0
0
75
0
0
9
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
9
17
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
84
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _