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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FLII
All Species:
16.97
Human Site:
S538
Identified Species:
33.94
UniProt:
Q13045
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13045
NP_002009.1
1269
144751
S538
L
K
T
F
L
D
D
S
G
S
L
N
W
E
I
Chimpanzee
Pan troglodytes
XP_511321
1458
164815
T755
D
C
Y
I
V
L
K
T
F
L
D
D
S
G
S
Rhesus Macaque
Macaca mulatta
XP_001094628
1256
143248
S537
L
K
T
F
L
D
D
S
G
S
L
N
W
E
I
Dog
Lupus familis
XP_536659
1147
130372
F503
T
I
W
Q
I
E
N
F
V
P
V
L
V
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJ28
1271
144785
S538
L
K
T
F
L
D
D
S
G
S
L
N
W
E
I
Rat
Rattus norvegicus
NP_001008280
1270
144839
S538
L
K
T
F
L
D
D
S
G
S
L
N
W
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025806
1265
144848
N537
L
K
T
F
L
D
E
N
G
S
L
S
W
E
I
Frog
Xenopus laevis
NP_001086319
1270
145779
L539
L
K
T
Y
L
D
S
L
G
A
L
H
W
E
I
Zebra Danio
Brachydanio rerio
XP_688770
1259
143734
N537
L
K
T
F
L
D
E
N
G
A
L
N
W
Q
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24020
1256
143664
L536
L
K
T
K
F
D
D
L
G
L
L
D
W
E
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34268
1257
144797
S547
L
K
T
T
R
E
A
S
G
Q
L
R
H
A
I
Sea Urchin
Strong. purpuratus
XP_790260
1140
130867
W500
D
S
S
Q
N
L
N
W
Q
I
F
Y
W
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.3
97.2
86.8
N.A.
95.1
95.1
N.A.
N.A.
87.7
82.8
83.6
N.A.
57.2
N.A.
51.1
50.5
Protein Similarity:
100
84.5
98.1
88
N.A.
96.8
96.7
N.A.
N.A.
93.3
91.8
91.4
N.A.
74.1
N.A.
69.9
67.9
P-Site Identity:
100
0
100
6.6
N.A.
100
100
N.A.
N.A.
80
66.6
73.3
N.A.
66.6
N.A.
46.6
6.6
P-Site Similarity:
100
20
100
33.3
N.A.
100
100
N.A.
N.A.
100
86.6
100
N.A.
73.3
N.A.
53.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
0
17
0
0
0
9
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
0
0
0
67
42
0
0
0
9
17
0
0
0
% D
% Glu:
0
0
0
0
0
17
17
0
0
0
0
0
0
67
9
% E
% Phe:
0
0
0
50
9
0
0
9
9
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
75
0
0
0
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% H
% Ile:
0
9
0
9
9
0
0
0
0
9
0
0
0
9
75
% I
% Lys:
0
75
0
9
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
75
0
0
0
59
17
0
17
0
17
75
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
17
17
0
0
0
42
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
17
0
0
0
0
9
9
0
0
0
9
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
0
9
9
0
0
0
9
42
0
42
0
9
9
0
9
% S
% Thr:
9
0
75
9
0
0
0
9
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
9
0
0
0
9
0
9
0
9
0
0
% V
% Trp:
0
0
9
0
0
0
0
9
0
0
0
0
75
0
0
% W
% Tyr:
0
0
9
9
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _