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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FLII All Species: 24.85
Human Site: S820 Identified Species: 49.7
UniProt: Q13045 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13045 NP_002009.1 1269 144751 S820 R P R H A T V S R S L E G T E
Chimpanzee Pan troglodytes XP_511321 1458 164815 S1008 R P R H A T V S R S L E G T E
Rhesus Macaque Macaca mulatta XP_001094628 1256 143248 S819 R P R H A T V S R S L E G T E
Dog Lupus familis XP_536659 1147 130372 L754 M K A D L T A L F L P R Q P P
Cat Felis silvestris
Mouse Mus musculus Q9JJ28 1271 144785 S820 R P R H T V V S R S L E G T E
Rat Rattus norvegicus NP_001008280 1270 144839 S820 R P R H T V V S R S L E G T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001025806 1265 144848 T819 R P K H A M V T R N L E G T E
Frog Xenopus laevis NP_001086319 1270 145779 I821 R P K H S I V I R N L E G T E
Zebra Danio Brachydanio rerio XP_688770 1259 143734 I819 R P K H A V V I R N L E G T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24020 1256 143664 M811 R P D Y A L V M R V P E G N E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34268 1257 144797 Y820 R P D Y A Q V Y R E T E G E E
Sea Urchin Strong. purpuratus XP_790260 1140 130867 S752 K L S Q E L C S M L N R P T N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.3 97.2 86.8 N.A. 95.1 95.1 N.A. N.A. 87.7 82.8 83.6 N.A. 57.2 N.A. 51.1 50.5
Protein Similarity: 100 84.5 98.1 88 N.A. 96.8 96.7 N.A. N.A. 93.3 91.8 91.4 N.A. 74.1 N.A. 69.9 67.9
P-Site Identity: 100 100 100 6.6 N.A. 86.6 86.6 N.A. N.A. 73.3 66.6 73.3 N.A. 53.3 N.A. 53.3 13.3
P-Site Similarity: 100 100 100 6.6 N.A. 86.6 86.6 N.A. N.A. 93.3 86.6 86.6 N.A. 60 N.A. 60 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 59 0 9 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 17 9 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 9 0 0 0 0 9 0 84 0 9 84 % E
% Phe: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 84 0 0 % G
% His: 0 0 0 67 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 9 0 17 0 0 0 0 0 0 0 % I
% Lys: 9 9 25 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 9 0 0 9 17 0 9 0 17 67 0 0 0 0 % L
% Met: 9 0 0 0 0 9 0 9 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 25 9 0 0 9 9 % N
% Pro: 0 84 0 0 0 0 0 0 0 0 17 0 9 9 9 % P
% Gln: 0 0 0 9 0 9 0 0 0 0 0 0 9 0 0 % Q
% Arg: 84 0 42 0 0 0 0 0 84 0 0 17 0 0 0 % R
% Ser: 0 0 9 0 9 0 0 50 0 42 0 0 0 0 0 % S
% Thr: 0 0 0 0 17 34 0 9 0 0 9 0 0 75 0 % T
% Val: 0 0 0 0 0 25 84 0 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 17 0 0 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _