KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COASY
All Species:
22.73
Human Site:
S278
Identified Species:
41.67
UniProt:
Q13057
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13057
NP_001035994.1
564
62329
S278
D
P
Y
G
P
A
G
S
D
P
S
L
E
F
L
Chimpanzee
Pan troglodytes
XP_001163123
564
62420
S278
D
P
Y
G
P
A
G
S
D
P
S
L
E
F
L
Rhesus Macaque
Macaca mulatta
XP_001109889
564
62448
S278
D
P
Y
G
P
A
G
S
D
P
S
L
E
F
L
Dog
Lupus familis
XP_537637
560
61750
S278
D
P
Y
G
P
A
G
S
N
P
S
L
E
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBL7
563
62005
S277
D
P
Y
G
P
A
G
S
D
P
T
L
E
F
L
Rat
Rattus norvegicus
NP_001006955
563
62169
S277
D
P
Y
G
P
A
G
S
D
P
T
L
E
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423303
225
24122
Frog
Xenopus laevis
NP_001086140
559
61844
C270
I
T
D
P
D
L
K
C
I
V
V
S
E
E
T
Zebra Danio
Brachydanio rerio
NP_001004577
554
61375
L270
P
S
I
T
E
P
E
L
Q
C
I
V
V
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647985
518
57623
V271
E
I
F
V
I
D
I
V
E
S
N
V
H
D
G
Honey Bee
Apis mellifera
XP_624486
327
37648
I84
D
I
H
I
I
K
I
I
T
D
E
D
H
K
E
Nematode Worm
Caenorhab. elegans
NP_490766
461
51130
L218
N
E
Q
G
M
S
Q
L
D
V
I
I
V
E
L
Sea Urchin
Strong. purpuratus
XP_784992
470
50844
D227
K
I
T
V
G
V
T
D
G
P
M
L
E
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.3
91.4
N.A.
86.8
85.6
N.A.
N.A.
24.6
58.1
51.5
N.A.
38.2
25.7
33.8
33.8
Protein Similarity:
100
99.6
98.7
95.5
N.A.
93.9
93
N.A.
N.A.
31.7
75.3
70.3
N.A.
55.5
41.1
51.9
51.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
0
6.6
0
N.A.
0
6.6
20
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
0
6.6
6.6
N.A.
33.3
13.3
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
47
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% C
% Asp:
54
0
8
0
8
8
0
8
47
8
0
8
0
8
0
% D
% Glu:
8
8
0
0
8
0
8
0
8
0
8
0
62
16
16
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
47
0
% F
% Gly:
0
0
0
54
8
0
47
0
8
0
0
0
0
0
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
16
0
0
% H
% Ile:
8
24
8
8
16
0
16
8
8
0
16
8
0
0
0
% I
% Lys:
8
0
0
0
0
8
8
0
0
0
0
0
0
8
8
% K
% Leu:
0
0
0
0
0
8
0
16
0
0
0
54
0
0
54
% L
% Met:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
8
0
8
0
0
8
0
% N
% Pro:
8
47
0
8
47
8
0
0
0
54
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
8
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
8
0
47
0
8
31
8
0
8
0
% S
% Thr:
0
8
8
8
0
0
8
0
8
0
16
0
0
0
8
% T
% Val:
0
0
0
16
0
8
0
8
0
16
8
16
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
47
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _