Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COASY All Species: 17.27
Human Site: Y349 Identified Species: 31.67
UniProt: Q13057 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13057 NP_001035994.1 564 62329 Y349 G N L L R P P Y E R P E L P T
Chimpanzee Pan troglodytes XP_001163123 564 62420 Y349 G N L L R P P Y E R P E L P T
Rhesus Macaque Macaca mulatta XP_001109889 564 62448 Y349 G N L L R P P Y E R P E L P T
Dog Lupus familis XP_537637 560 61750 Y349 G N L L Q P P Y K R P E L P T
Cat Felis silvestris
Mouse Mus musculus Q9DBL7 563 62005 N348 G N L L Q P P N E R P E L P S
Rat Rattus norvegicus NP_001006955 563 62169 N348 G N L L Q P P N E R P E L P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423303 225 24122 L47 A K L R E F L L D V Q P S V L
Frog Xenopus laevis NP_001086140 559 61844 K335 G T L L R P L K V N S S I P A
Zebra Danio Brachydanio rerio NP_001004577 554 61375 S337 G T L L K P P S P E L D L P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647985 518 57623 A336 E R L A N M G A H V I D C D K
Honey Bee Apis mellifera XP_624486 327 37648 A149 K L K K L G A A L V N C D K I
Nematode Worm Caenorhab. elegans NP_490766 461 51130 K283 S G K S H I G K Y L R E T H N
Sea Urchin Strong. purpuratus XP_784992 470 50844 T292 C I V V S E E T R K G G D S V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.3 91.4 N.A. 86.8 85.6 N.A. N.A. 24.6 58.1 51.5 N.A. 38.2 25.7 33.8 33.8
Protein Similarity: 100 99.6 98.7 95.5 N.A. 93.9 93 N.A. N.A. 31.7 75.3 70.3 N.A. 55.5 41.1 51.9 51.2
P-Site Identity: 100 100 100 86.6 N.A. 80 80 N.A. N.A. 6.6 40 46.6 N.A. 6.6 0 6.6 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 13.3 46.6 60 N.A. 13.3 0 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 0 0 8 16 0 0 0 0 0 0 8 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 0 16 16 8 0 % D
% Glu: 8 0 0 0 8 8 8 0 39 8 0 54 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 62 8 0 0 0 8 16 0 0 0 8 8 0 0 0 % G
% His: 0 0 0 0 8 0 0 0 8 0 0 0 0 8 0 % H
% Ile: 0 8 0 0 0 8 0 0 0 0 8 0 8 0 8 % I
% Lys: 8 8 16 8 8 0 0 16 8 8 0 0 0 8 8 % K
% Leu: 0 8 77 62 8 0 16 8 8 8 8 0 54 0 16 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 47 0 0 8 0 0 16 0 8 8 0 0 0 8 % N
% Pro: 0 0 0 0 0 62 54 0 8 0 47 8 0 62 0 % P
% Gln: 0 0 0 0 24 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 8 0 8 31 0 0 0 8 47 8 0 0 0 0 % R
% Ser: 8 0 0 8 8 0 0 8 0 0 8 8 8 8 16 % S
% Thr: 0 16 0 0 0 0 0 8 0 0 0 0 8 0 31 % T
% Val: 0 0 8 8 0 0 0 0 8 24 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 31 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _