Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACACA All Species: 21.21
Human Site: S1259 Identified Species: 46.67
UniProt: Q13085 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13085 NP_942131.1 2346 265554 S1259 V M G C F S D S P P Q S P T F
Chimpanzee Pan troglodytes XP_511428 2532 285118 S1445 V M G C F S D S P P Q S P T F
Rhesus Macaque Macaca mulatta XP_001111823 2383 270071 S1296 V M S C F S D S P P Q S P T F
Dog Lupus familis XP_548250 2323 262646 F1258 S P P Q S P T F P E A G H T S
Cat Felis silvestris
Mouse Mus musculus Q5SWU9 2345 265238 S1258 I M G C F C D S P P Q S P T F
Rat Rattus norvegicus P11497 2345 265175 S1258 V M G C F C D S P P Q S P T F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508230 2450 275669 A1394 D C P L F H E A R S T L Y C E
Chicken Gallus gallus P11029 2324 262701 F1258 S P P Q S P T F P E A G H A S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919815 2349 265001 S1259 V L S C F S D S P P S T P T F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610342 2482 278578 A1395 K V L E A V E A A D S I S D S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q00955 2233 250335 H1200 S L E V I P R H Q S S S N G P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.6 98.1 97.2 N.A. 97.5 97.3 N.A. 72.9 92.4 N.A. 87.1 N.A. 57.9 N.A. N.A. N.A.
Protein Similarity: 100 92.6 98.2 98.1 N.A. 99 99 N.A. 83.2 95.8 N.A. 93 N.A. 72.7 N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 13.3 N.A. 86.6 93.3 N.A. 6.6 6.6 N.A. 73.3 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 13.3 N.A. 93.3 93.3 N.A. 20 6.6 N.A. 86.6 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 44.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 62.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 19 10 0 19 0 0 10 0 % A
% Cys: 0 10 0 55 0 19 0 0 0 0 0 0 0 10 0 % C
% Asp: 10 0 0 0 0 0 55 0 0 10 0 0 0 10 0 % D
% Glu: 0 0 10 10 0 0 19 0 0 19 0 0 0 0 10 % E
% Phe: 0 0 0 0 64 0 0 19 0 0 0 0 0 0 55 % F
% Gly: 0 0 37 0 0 0 0 0 0 0 0 19 0 10 0 % G
% His: 0 0 0 0 0 10 0 10 0 0 0 0 19 0 0 % H
% Ile: 10 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 19 10 10 0 0 0 0 0 0 0 10 0 0 0 % L
% Met: 0 46 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 19 28 0 0 28 0 0 73 55 0 0 55 0 10 % P
% Gln: 0 0 0 19 0 0 0 0 10 0 46 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % R
% Ser: 28 0 19 0 19 37 0 55 0 19 28 55 10 0 28 % S
% Thr: 0 0 0 0 0 0 19 0 0 0 10 10 0 64 0 % T
% Val: 46 10 0 10 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _