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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDIA2 All Species: 0.91
Human Site: S28 Identified Species: 1.43
UniProt: Q13087 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13087 NP_006840.2 525 58206 S28 G Q E Q G A R S P S E E P P E
Chimpanzee Pan troglodytes XP_001164396 508 57114 L29 E E D H V L V L R K S N F A E
Rhesus Macaque Macaca mulatta XP_001084171 524 57993 P28 Q E Q G P K S P S E E P P E E
Dog Lupus familis XP_540488 510 57398 L29 P E E E D H V L V L H K G N F
Cat Felis silvestris
Mouse Mus musculus P09103 509 57125 L29 L E E E D N V L V L K K S N F
Rat Rattus norvegicus P04785 509 56933 L29 L E E E D N V L V L K K S N F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517226 512 56706 L31 P E E E D H V L V L K K S N F
Chicken Gallus gallus P09102 515 57391 V33 E E E D G V L V L R A A N F E
Frog Xenopus laevis NP_001083648 526 60161 E28 G Q N D A T E E P T K S S S E
Zebra Danio Brachydanio rerio NP_998529 509 56615 K28 E E D V L V L K K S N F E E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54399 496 55763 V31 K V E E G V L V A T V D N F K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17770 493 55134 L28 E E E N V I V L T K D N F D E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P52588 513 57078 A28 A R A E E E P A A A A E G E A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRG3 508 56346 T33 E T K E F V L T L D H S N F T
Baker's Yeast Sacchar. cerevisiae P17967 522 58209 A28 F A Q Q E A V A P E D S A V V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.2 93.9 46.6 N.A. 46.6 46.8 N.A. 46.4 46.8 50 45.5 N.A. 40.7 N.A. 41.7 N.A.
Protein Similarity: 100 64.5 96.5 64.7 N.A. 64.9 65.1 N.A. 64.7 66 68.2 64.7 N.A. 60.7 N.A. 59.8 N.A.
P-Site Identity: 100 6.6 20 6.6 N.A. 6.6 6.6 N.A. 6.6 20 26.6 6.6 N.A. 13.3 N.A. 13.3 N.A.
P-Site Similarity: 100 20 33.3 26.6 N.A. 33.3 33.3 N.A. 33.3 26.6 40 20 N.A. 40 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. 31.4 N.A. 33.7 26.2 N.A.
Protein Similarity: N.A. 50.4 N.A. 53.3 45.9 N.A.
P-Site Identity: N.A. 6.6 N.A. 0 20 N.A.
P-Site Similarity: N.A. 33.3 N.A. 20 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 0 7 14 0 14 14 7 14 7 7 7 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 14 14 27 0 0 0 0 7 14 7 0 7 0 % D
% Glu: 34 60 54 47 14 7 7 7 0 14 14 14 7 20 40 % E
% Phe: 7 0 0 0 7 0 0 0 0 0 0 7 14 20 27 % F
% Gly: 14 0 0 7 20 0 0 0 0 0 0 0 14 0 0 % G
% His: 0 0 0 7 0 14 0 0 0 0 14 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % I
% Lys: 7 0 7 0 0 7 0 7 7 14 27 27 0 0 7 % K
% Leu: 14 0 0 0 7 7 27 40 14 27 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 7 0 14 0 0 0 0 7 14 20 27 0 % N
% Pro: 14 0 0 0 7 0 7 7 20 0 0 7 14 7 0 % P
% Gln: 7 14 14 14 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 7 0 0 0 0 7 0 7 7 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 7 7 7 14 7 20 27 7 0 % S
% Thr: 0 7 0 0 0 7 0 7 7 14 0 0 0 0 7 % T
% Val: 0 7 0 7 14 27 47 14 27 0 7 0 0 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _