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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA2
All Species:
6.36
Human Site:
T486
Identified Species:
10
UniProt:
Q13087
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13087
NP_006840.2
525
58206
T486
K
S
T
R
D
L
E
T
F
S
K
F
L
D
N
Chimpanzee
Pan troglodytes
XP_001164396
508
57114
G465
N
G
E
R
T
L
D
G
F
K
K
F
L
E
S
Rhesus Macaque
Macaca mulatta
XP_001084171
524
57993
T485
K
S
A
R
D
L
E
T
L
S
K
F
L
D
N
Dog
Lupus familis
XP_540488
510
57398
G467
N
G
E
R
T
L
D
G
F
K
K
F
L
E
S
Cat
Felis silvestris
Mouse
Mus musculus
P09103
509
57125
G467
N
G
E
R
T
L
D
G
F
K
K
F
L
E
S
Rat
Rattus norvegicus
P04785
509
56933
G467
N
G
E
R
T
L
D
G
F
K
K
F
L
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517226
512
56706
G469
N
G
E
R
T
L
E
G
F
T
K
F
L
E
S
Chicken
Gallus gallus
P09102
515
57391
G470
N
G
E
R
T
L
E
G
F
K
K
F
L
E
S
Frog
Xenopus laevis
NP_001083648
526
60161
L488
T
K
E
R
T
V
E
L
F
S
A
F
I
D
S
Zebra Danio
Brachydanio rerio
NP_998529
509
56615
G463
N
G
E
R
T
L
D
G
F
T
K
F
L
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
I443
K
I
S
S
F
P
T
I
K
Y
F
R
K
E
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17770
493
55134
I439
K
I
Q
S
F
P
T
I
K
F
F
P
A
G
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
I476
S
G
R
T
A
D
D
I
V
D
F
I
K
K
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
D470
E
G
D
R
T
K
E
D
F
I
N
F
V
E
K
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
S475
Q
G
S
R
S
L
D
S
L
F
D
F
I
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.2
93.9
46.6
N.A.
46.6
46.8
N.A.
46.4
46.8
50
45.5
N.A.
40.7
N.A.
41.7
N.A.
Protein Similarity:
100
64.5
96.5
64.7
N.A.
64.9
65.1
N.A.
64.7
66
68.2
64.7
N.A.
60.7
N.A.
59.8
N.A.
P-Site Identity:
100
40
86.6
40
N.A.
40
40
N.A.
46.6
46.6
40
40
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
60
86.6
60
N.A.
60
60
N.A.
66.6
60
60
66.6
N.A.
26.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
31.4
N.A.
33.7
26.2
N.A.
Protein Similarity:
N.A.
50.4
N.A.
53.3
45.9
N.A.
P-Site Identity:
N.A.
0
N.A.
26.6
20
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
46.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
0
0
0
0
0
7
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
14
7
47
7
0
7
7
0
0
20
7
% D
% Glu:
7
0
54
0
0
0
40
0
0
0
0
0
0
60
7
% E
% Phe:
0
0
0
0
14
0
0
0
67
14
20
80
0
0
0
% F
% Gly:
0
67
0
0
0
0
0
47
0
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
14
0
0
0
0
0
20
0
7
0
7
14
0
0
% I
% Lys:
27
7
0
0
0
7
0
0
14
34
60
0
14
14
7
% K
% Leu:
0
0
0
0
0
67
0
7
14
0
0
0
60
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
47
0
0
0
0
0
0
0
0
0
7
0
0
0
14
% N
% Pro:
0
0
0
0
0
14
0
0
0
0
0
7
0
0
0
% P
% Gln:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
80
0
0
0
0
0
0
0
7
0
0
0
% R
% Ser:
7
14
14
14
7
0
0
7
0
20
0
0
0
0
67
% S
% Thr:
7
0
7
7
60
0
14
14
0
14
0
0
0
0
0
% T
% Val:
0
0
0
0
0
7
0
0
7
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _