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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA2
All Species:
9.09
Human Site:
Y117
Identified Species:
14.29
UniProt:
Q13087
Number Species:
14
Phosphosite Substitution
Charge Score:
0.57
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13087
NP_006840.2
525
58206
Y117
E
E
F
G
V
T
E
Y
P
T
L
K
F
F
R
Chimpanzee
Pan troglodytes
XP_001164396
508
57114
E115
G
D
T
A
S
P
K
E
Y
T
A
G
R
E
A
Rhesus Macaque
Macaca mulatta
XP_001084171
524
57993
Y116
E
E
F
G
V
T
E
Y
P
T
L
K
F
F
R
Dog
Lupus familis
XP_540488
510
57398
E123
R
E
Y
T
A
G
R
E
A
E
D
I
V
N
W
Cat
Felis silvestris
Mouse
Mus musculus
P09103
509
57125
E117
G
D
T
A
S
P
K
E
Y
T
A
G
R
E
A
Rat
Rattus norvegicus
P04785
509
56933
E117
G
D
T
A
S
P
K
E
Y
T
A
G
R
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517226
512
56706
E119
G
D
T
A
S
P
K
E
Y
T
A
G
R
E
A
Chicken
Gallus gallus
P09102
515
57391
E120
G
D
K
A
A
P
R
E
Y
T
A
G
R
E
A
Frog
Xenopus laevis
NP_001083648
526
60161
Y121
T
E
F
N
V
N
G
Y
P
T
L
K
F
F
K
Zebra Danio
Brachydanio rerio
NP_998529
509
56615
E113
G
E
K
G
N
P
K
E
Y
S
A
G
R
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
A123
Y
S
G
G
R
Q
A
A
D
I
I
A
W
V
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17770
493
55134
H118
E
Y
N
G
G
R
D
H
D
S
I
I
A
W
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
F111
T
K
Y
E
I
Q
G
F
P
T
I
K
I
F
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
D121
N
G
G
K
S
V
Q
D
Y
N
G
P
R
E
A
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
Y122
D
V
N
N
S
I
D
Y
E
G
P
R
T
A
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.2
93.9
46.6
N.A.
46.6
46.8
N.A.
46.4
46.8
50
45.5
N.A.
40.7
N.A.
41.7
N.A.
Protein Similarity:
100
64.5
96.5
64.7
N.A.
64.9
65.1
N.A.
64.7
66
68.2
64.7
N.A.
60.7
N.A.
59.8
N.A.
P-Site Identity:
100
6.6
100
6.6
N.A.
6.6
6.6
N.A.
6.6
6.6
66.6
13.3
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
20
100
13.3
N.A.
20
20
N.A.
20
13.3
73.3
26.6
N.A.
20
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
31.4
N.A.
33.7
26.2
N.A.
Protein Similarity:
N.A.
50.4
N.A.
53.3
45.9
N.A.
P-Site Identity:
N.A.
33.3
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
34
14
0
7
7
7
0
40
7
7
7
47
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
34
0
0
0
0
14
7
14
0
7
0
0
0
0
% D
% Glu:
20
34
0
7
0
0
14
47
7
7
0
0
0
40
7
% E
% Phe:
0
0
20
0
0
0
0
7
0
0
0
0
20
27
0
% F
% Gly:
40
7
14
34
7
7
14
0
0
7
7
40
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
7
0
0
0
7
20
14
7
0
0
% I
% Lys:
0
7
14
7
0
0
34
0
0
0
0
27
0
0
7
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
14
14
7
7
0
0
0
7
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
40
0
0
27
0
7
7
0
0
0
% P
% Gln:
0
0
0
0
0
14
7
0
0
0
0
0
0
7
0
% Q
% Arg:
7
0
0
0
7
7
14
0
0
0
0
7
47
0
20
% R
% Ser:
0
7
0
0
40
0
0
0
0
14
0
0
0
0
0
% S
% Thr:
14
0
27
7
0
14
0
0
0
60
0
0
7
0
7
% T
% Val:
0
7
0
0
20
7
0
0
0
0
0
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
7
% W
% Tyr:
7
7
14
0
0
0
0
27
47
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _