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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDIA2 All Species: 4.55
Human Site: Y347 Identified Species: 7.14
UniProt: Q13087 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.43
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13087 NP_006840.2 525 58206 Y347 N L E T T K K Y A P V D G G P
Chimpanzee Pan troglodytes XP_001164396 508 57114 K326 T L E E E M T K Y K P E S E E
Rhesus Macaque Macaca mulatta XP_001084171 524 57993 Y346 N V E T T K K Y A P V D G G P
Dog Lupus familis XP_540488 510 57398 K328 T L E E E M T K Y K P E S T E
Cat Felis silvestris
Mouse Mus musculus P09103 509 57125 K328 T L E E E M T K Y K P E S D E
Rat Rattus norvegicus P04785 509 56933 K328 T L E E E M T K Y K P E S D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517226 512 56706 K330 T L E E E M T K Y K P E S D E
Chicken Gallus gallus P09102 515 57391 K331 T L E E E M T K Y K P E S D D
Frog Xenopus laevis NP_001083648 526 60161 K349 I N L E S V K K Y V F N A P E
Zebra Danio Brachydanio rerio NP_998529 509 56615 K324 T L E E E M T K Y K P E S S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54399 496 55763 F304 D H T R I F E F F G M N K E E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17770 493 55134 F300 E N A R I M E F F G L K K D E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P52588 513 57078 D337 L I L I Q D G D S K K F L K V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRG3 508 56346 D331 L I I I Q T P D N K K Y L K V
Baker's Yeast Sacchar. cerevisiae P17967 522 58209 F335 P Q L S E E A F D E L S D K I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.2 93.9 46.6 N.A. 46.6 46.8 N.A. 46.4 46.8 50 45.5 N.A. 40.7 N.A. 41.7 N.A.
Protein Similarity: 100 64.5 96.5 64.7 N.A. 64.9 65.1 N.A. 64.7 66 68.2 64.7 N.A. 60.7 N.A. 59.8 N.A.
P-Site Identity: 100 13.3 93.3 13.3 N.A. 13.3 13.3 N.A. 13.3 13.3 6.6 13.3 N.A. 0 N.A. 0 N.A.
P-Site Similarity: 100 20 100 20 N.A. 20 20 N.A. 20 20 20 20 N.A. 33.3 N.A. 20 N.A.
Percent
Protein Identity: N.A. 31.4 N.A. 33.7 26.2 N.A.
Protein Similarity: N.A. 50.4 N.A. 53.3 45.9 N.A.
P-Site Identity: N.A. 0 N.A. 0 0 N.A.
P-Site Similarity: N.A. 13.3 N.A. 6.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 7 0 14 0 0 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 7 0 14 7 0 0 14 7 34 7 % D
% Glu: 7 0 60 54 54 7 14 0 0 7 0 47 0 14 60 % E
% Phe: 0 0 0 0 0 7 0 20 14 0 7 7 0 0 0 % F
% Gly: 0 0 0 0 0 0 7 0 0 14 0 0 14 14 0 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 14 7 14 14 0 0 0 0 0 0 0 0 0 7 % I
% Lys: 0 0 0 0 0 14 20 54 0 60 14 7 14 20 0 % K
% Leu: 14 54 20 0 0 0 0 0 0 0 14 0 14 0 0 % L
% Met: 0 0 0 0 0 54 0 0 0 0 7 0 0 0 0 % M
% Asn: 14 14 0 0 0 0 0 0 7 0 0 14 0 0 0 % N
% Pro: 7 0 0 0 0 0 7 0 0 14 47 0 0 7 14 % P
% Gln: 0 7 0 0 14 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 7 7 0 0 0 7 0 0 7 47 7 0 % S
% Thr: 47 0 7 14 14 7 47 0 0 0 0 0 0 7 0 % T
% Val: 0 7 0 0 0 7 0 0 0 7 14 0 0 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 14 54 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _