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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA2
All Species:
4.55
Human Site:
Y375
Identified Species:
7.14
UniProt:
Q13087
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13087
NP_006840.2
525
58206
Y375
L
N
G
Q
V
K
P
Y
L
L
S
Q
E
I
P
Chimpanzee
Pan troglodytes
XP_001164396
508
57114
H354
L
E
G
K
I
K
P
H
L
M
S
Q
E
L
P
Rhesus Macaque
Macaca mulatta
XP_001084171
524
57993
Y374
L
N
G
Q
V
K
P
Y
L
L
S
Q
E
V
P
Dog
Lupus familis
XP_540488
510
57398
H356
L
E
G
K
I
K
P
H
L
M
S
Q
E
L
P
Cat
Felis silvestris
Mouse
Mus musculus
P09103
509
57125
H356
L
E
G
K
I
K
P
H
L
M
S
Q
E
V
P
Rat
Rattus norvegicus
P04785
509
56933
H356
L
E
G
K
I
K
P
H
L
M
S
Q
E
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517226
512
56706
H358
L
E
G
K
V
K
P
H
L
M
S
Q
D
L
P
Chicken
Gallus gallus
P09102
515
57391
H359
L
E
G
K
I
K
P
H
L
M
S
Q
D
L
P
Frog
Xenopus laevis
NP_001083648
526
60161
N377
L
E
G
N
V
K
Q
N
L
M
S
E
E
I
P
Zebra Danio
Brachydanio rerio
NP_998529
509
56615
H352
V
E
G
T
L
K
P
H
L
M
S
Q
D
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
D332
A
K
Y
K
P
E
S
D
D
L
S
A
E
T
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17770
493
55134
E328
T
K
F
K
P
D
F
E
E
I
T
T
E
N
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
P365
Y
F
D
G
K
L
T
P
F
R
N
S
E
P
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
V359
F
Q
D
G
K
V
A
V
H
K
K
S
Q
P
I
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
P363
F
L
K
G
D
A
S
P
I
V
K
S
Q
E
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.2
93.9
46.6
N.A.
46.6
46.8
N.A.
46.4
46.8
50
45.5
N.A.
40.7
N.A.
41.7
N.A.
Protein Similarity:
100
64.5
96.5
64.7
N.A.
64.9
65.1
N.A.
64.7
66
68.2
64.7
N.A.
60.7
N.A.
59.8
N.A.
P-Site Identity:
100
60
93.3
60
N.A.
60
60
N.A.
60
53.3
60
53.3
N.A.
20
N.A.
6.6
N.A.
P-Site Similarity:
100
93.3
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
73.3
86.6
N.A.
33.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
31.4
N.A.
33.7
26.2
N.A.
Protein Similarity:
N.A.
50.4
N.A.
53.3
45.9
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
7
7
0
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
14
0
7
7
0
7
7
0
0
0
20
0
0
% D
% Glu:
0
54
0
0
0
7
0
7
7
0
0
7
67
7
0
% E
% Phe:
14
7
7
0
0
0
7
0
7
0
0
0
0
0
0
% F
% Gly:
0
0
67
20
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
47
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
34
0
0
0
7
7
0
0
0
20
34
% I
% Lys:
0
14
7
54
14
67
0
0
0
7
14
0
0
0
0
% K
% Leu:
60
7
0
0
7
7
0
0
67
20
0
0
0
34
0
% L
% Met:
0
0
0
0
0
0
0
0
0
54
0
0
0
0
0
% M
% Asn:
0
14
0
7
0
0
0
7
0
0
7
0
0
7
0
% N
% Pro:
0
0
0
0
14
0
60
14
0
0
0
0
0
14
67
% P
% Gln:
0
7
0
14
0
0
7
0
0
0
0
60
14
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
14
0
0
0
74
20
0
0
0
% S
% Thr:
7
0
0
7
0
0
7
0
0
0
7
7
0
7
0
% T
% Val:
7
0
0
0
27
7
0
7
0
7
0
0
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
0
0
0
14
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _