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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP4 All Species: 6.67
Human Site: S936 Identified Species: 16.3
UniProt: Q13107 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13107 NP_003354.2 963 108565 S936 K T P S L S S S G S S D G G T
Chimpanzee Pan troglodytes XP_001163445 962 108358 S935 K T P S L S S S G S S D G G T
Rhesus Macaque Macaca mulatta XP_001116743 981 112401 R946 T G F F P L D R E T K G A S A
Dog Lupus familis XP_533829 1037 116252 F1009 K T P S L A S F P G S S E G G
Cat Felis silvestris
Mouse Mus musculus P35123 962 108262 F935 S T S S L G S F P G S D G G V
Rat Rattus norvegicus Q6J1Y9 1357 150284 V1257 Y R R R N S P V E R P P R A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505377 988 112483 G962 R A P S S L P G F S E E T L S
Chicken Gallus gallus
Frog Xenopus laevis NP_001082452 975 110692 S949 N V D C K N S S P A A S I G T
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q93Y01 910 102631 N877 D S H V S S V N E S E I K N S
Baker's Yeast Sacchar. cerevisiae P39538 1254 143174 L1122 N G L G S S K L Q E I I Q K S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 58.8 88.3 N.A. 90.4 26.7 N.A. 75.6 N.A. 68.5 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 73.8 90 N.A. 94.3 40.4 N.A. 84.5 N.A. 80.9 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 53.3 N.A. 53.3 6.6 N.A. 20 N.A. 26.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 6.6 60 N.A. 53.3 6.6 N.A. 40 N.A. 46.6 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 36.1 26 N.A.
Protein Similarity: N.A. N.A. N.A. 54.1 40.8 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 10 0 0 0 10 10 0 10 10 20 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 0 0 10 0 0 0 0 30 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 30 10 20 10 10 0 0 % E
% Phe: 0 0 10 10 0 0 0 20 10 0 0 0 0 0 0 % F
% Gly: 0 20 0 10 0 10 0 10 20 20 0 10 30 50 10 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 20 10 0 0 % I
% Lys: 30 0 0 0 10 0 10 0 0 0 10 0 10 10 0 % K
% Leu: 0 0 10 0 40 20 0 10 0 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 20 0 0 0 10 10 0 10 0 0 0 0 0 10 0 % N
% Pro: 0 0 40 0 10 0 20 0 30 0 10 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % Q
% Arg: 10 10 10 10 0 0 0 10 0 10 0 0 10 0 0 % R
% Ser: 10 10 10 50 30 50 50 30 0 40 40 20 0 10 30 % S
% Thr: 10 40 0 0 0 0 0 0 0 10 0 0 10 0 30 % T
% Val: 0 10 0 10 0 0 10 10 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _