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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHAF1A All Species: 9.39
Human Site: S141 Identified Species: 29.52
UniProt: Q13111 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13111 NP_005474.2 956 106926 S141 N K L N S E A S P S R E A I N
Chimpanzee Pan troglodytes XP_512286 1029 114977 S214 N K L N S E A S P S R E A V N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542156 825 92088 V127 F K G K V P V V V L Q D I L A
Cat Felis silvestris
Mouse Mus musculus Q9QWF0 911 101917 S130 P E G H S E L S P D T A G V V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5R1T0 937 105114 S135 V S F D S K A S S A A L T N G
Frog Xenopus laevis A0JMT0 885 99651 L135 N G E S R A Q L A N G T V S P
Zebra Danio Brachydanio rerio A0JMK9 863 97204 T176 A L P L L D I T Q D S D T E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789313 1227 135011 A184 D F E P P K S A T K K S K A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92 N.A. 65.7 N.A. 65.6 N.A. N.A. N.A. 56.9 45.8 43.5 N.A. N.A. N.A. N.A. 25.1
Protein Similarity: 100 92.3 N.A. 72.2 N.A. 75.3 N.A. N.A. N.A. 71.3 60.9 57.2 N.A. N.A. N.A. N.A. 41
P-Site Identity: 100 93.3 N.A. 6.6 N.A. 26.6 N.A. N.A. N.A. 20 6.6 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 N.A. 26.6 N.A. 46.6 N.A. N.A. N.A. 40 20 20 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 0 0 13 38 13 13 13 13 13 25 13 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 0 0 13 0 13 0 0 0 25 0 25 0 0 0 % D
% Glu: 0 13 25 0 0 38 0 0 0 0 0 25 0 13 25 % E
% Phe: 13 13 13 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 13 25 0 0 0 0 0 0 0 13 0 13 0 13 % G
% His: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 13 0 0 0 0 0 13 13 0 % I
% Lys: 0 38 0 13 0 25 0 0 0 13 13 0 13 0 0 % K
% Leu: 0 13 25 13 13 0 13 13 0 13 0 13 0 13 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 38 0 0 25 0 0 0 0 0 13 0 0 0 13 25 % N
% Pro: 13 0 13 13 13 13 0 0 38 0 0 0 0 0 13 % P
% Gln: 0 0 0 0 0 0 13 0 13 0 13 0 0 0 0 % Q
% Arg: 0 0 0 0 13 0 0 0 0 0 25 0 0 0 0 % R
% Ser: 0 13 0 13 50 0 13 50 13 25 13 13 0 13 0 % S
% Thr: 0 0 0 0 0 0 0 13 13 0 13 13 25 0 0 % T
% Val: 13 0 0 0 13 0 13 13 13 0 0 0 13 25 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _