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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHAF1B All Species: 8.18
Human Site: S403 Identified Species: 12
UniProt: Q13112 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13112 NP_005432.1 559 61493 S403 D T A K K T K S Q T H R G S S
Chimpanzee Pan troglodytes XP_525468 559 61460 S403 D T A K K T K S Q T H R G S S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544875 668 72082 P513 G I P L K E K P V L S M R T P
Cat Felis silvestris
Mouse Mus musculus Q9D0N7 572 63114 N410 D T A K K A K N Q T H Q G S S
Rat Rattus norvegicus NP_001019912 572 62715 N410 D T A K K T K N Q N P Q G S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512498 575 62833 Q411 V E K K A K S Q A Q R G V S P
Chicken Gallus gallus Q5R1S9 566 62559 K410 V V T E K K V K K S Q P N K V
Frog Xenopus laevis Q8QFR2 1013 112021 R570 L D S R F T E R S K A T S G T
Zebra Danio Brachydanio rerio NP_998177 236 26626 A82 S P T A E V L A S G G D D A A
Tiger Blowfish Takifugu rubipres O42611 1025 111838 S489 N S A P I L P S G S S M S N Q
Fruit Fly Dros. melanogaster NP_610589 747 83376 L457 T E V G E P E L D A E N D S S
Honey Bee Apis mellifera XP_624307 452 51453 C298 E C T I A V R C C P L Y F E L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001191151 639 69080 S441 S K S P N Q Q S V S T G V A A
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001132835 506 55177 A352 D I A W S S D A K Y L A V S S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_974991 487 54088 I333 D T E C V A P I A V L A G L H
Baker's Yeast Sacchar. cerevisiae Q04199 468 51234 P314 N R P A I R I P S L K K P A L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 73.8 N.A. 82.3 82.6 N.A. 75.6 72.7 20.9 33.6 20.6 35.7 38.6 N.A. 44.1
Protein Similarity: 100 99.8 N.A. 76.3 N.A. 88.4 88.4 N.A. 82 81.4 33 38.4 31.7 49.6 56.1 N.A. 58.2
P-Site Identity: 100 100 N.A. 13.3 N.A. 80 73.3 N.A. 13.3 6.6 6.6 0 13.3 13.3 0 N.A. 6.6
P-Site Similarity: 100 100 N.A. 20 N.A. 93.3 86.6 N.A. 13.3 26.6 33.3 26.6 40 26.6 13.3 N.A. 40
Percent
Protein Identity: N.A. 37.2 N.A. 35.6 25.7 N.A.
Protein Similarity: N.A. 53.1 N.A. 54.3 42.9 N.A.
P-Site Identity: N.A. 26.6 N.A. 20 0 N.A.
P-Site Similarity: N.A. 46.6 N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 38 13 13 13 0 13 13 7 7 13 0 19 13 % A
% Cys: 0 7 0 7 0 0 0 7 7 0 0 0 0 0 0 % C
% Asp: 38 7 0 0 0 0 7 0 7 0 0 7 13 0 0 % D
% Glu: 7 13 7 7 13 7 13 0 0 0 7 0 0 7 0 % E
% Phe: 0 0 0 0 7 0 0 0 0 0 0 0 7 0 0 % F
% Gly: 7 0 0 7 0 0 0 0 7 7 7 13 32 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 7 % H
% Ile: 0 13 0 7 13 0 7 7 0 0 0 0 0 0 0 % I
% Lys: 0 7 7 32 38 13 32 7 13 7 7 7 0 7 0 % K
% Leu: 7 0 0 7 0 7 7 7 0 13 19 0 0 7 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % M
% Asn: 13 0 0 0 7 0 0 13 0 7 0 7 7 7 0 % N
% Pro: 0 7 13 13 0 7 13 13 0 7 7 7 7 0 13 % P
% Gln: 0 0 0 0 0 7 7 7 25 7 7 13 0 0 7 % Q
% Arg: 0 7 0 7 0 7 7 7 0 0 7 13 7 0 0 % R
% Ser: 13 7 13 0 7 7 7 25 19 19 13 0 13 44 38 % S
% Thr: 7 32 19 0 0 25 0 0 0 19 7 7 0 7 7 % T
% Val: 13 7 7 0 7 13 7 0 13 7 0 0 19 0 7 % V
% Trp: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _