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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHAF1B All Species: 16.06
Human Site: S464 Identified Species: 23.56
UniProt: Q13112 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13112 NP_005432.1 559 61493 S464 K S P L P G P S E E K T L Q P
Chimpanzee Pan troglodytes XP_525468 559 61460 S464 K S P L P G P S E E K T L Q P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544875 668 72082 E574 A P A A H S E E K A A L Q P S
Cat Felis silvestris
Mouse Mus musculus Q9D0N7 572 63114 S471 K S P L P Q P S E E K T L Q P
Rat Rattus norvegicus NP_001019912 572 62715 S471 K S P L P R P S E E K T L Q P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512498 575 62833 E472 S A T P P S E E R R D P Q P G
Chicken Gallus gallus Q5R1S9 566 62559 A471 E R K I S Q P A S Q S T K V N
Frog Xenopus laevis Q8QFR2 1013 112021 D631 R K G E A D A D L A E K R K K
Zebra Danio Brachydanio rerio NP_998177 236 26626 N143 I S W T S D G N F M A S G S V
Tiger Blowfish Takifugu rubipres O42611 1025 111838 S550 K S C L L L T S A S K I E P M
Fruit Fly Dros. melanogaster NP_610589 747 83376 G518 P R K P E D K G N S E S S K P
Honey Bee Apis mellifera XP_624307 452 51453 D359 L T D V A W S D D G R I L I A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001191151 639 69080 T502 S P P S N Q P T N S S S S P P
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001132835 506 55177 L413 V D N S A N K L K M E A S P V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_974991 487 54088 K394 P V D G E E K K H D L E K G D
Baker's Yeast Sacchar. cerevisiae Q04199 468 51234 P375 V G N I H Y S P I T D L A W S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 73.8 N.A. 82.3 82.6 N.A. 75.6 72.7 20.9 33.6 20.6 35.7 38.6 N.A. 44.1
Protein Similarity: 100 99.8 N.A. 76.3 N.A. 88.4 88.4 N.A. 82 81.4 33 38.4 31.7 49.6 56.1 N.A. 58.2
P-Site Identity: 100 100 N.A. 0 N.A. 93.3 93.3 N.A. 6.6 13.3 0 6.6 33.3 6.6 6.6 N.A. 20
P-Site Similarity: 100 100 N.A. 6.6 N.A. 93.3 93.3 N.A. 13.3 40 20 20 33.3 26.6 33.3 N.A. 33.3
Percent
Protein Identity: N.A. 37.2 N.A. 35.6 25.7 N.A.
Protein Similarity: N.A. 53.1 N.A. 54.3 42.9 N.A.
P-Site Identity: N.A. 0 N.A. 0 0 N.A.
P-Site Similarity: N.A. 13.3 N.A. 6.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 7 19 0 7 7 7 13 13 7 7 0 7 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 13 0 0 19 0 13 7 7 13 0 0 0 7 % D
% Glu: 7 0 0 7 13 7 13 13 25 25 19 7 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % F
% Gly: 0 7 7 7 0 13 7 7 0 7 0 0 7 7 7 % G
% His: 0 0 0 0 13 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 7 0 0 13 0 0 0 0 7 0 0 13 0 7 0 % I
% Lys: 32 7 13 0 0 0 19 7 13 0 32 7 13 13 7 % K
% Leu: 7 0 0 32 7 7 0 7 7 0 7 13 32 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 7 % M
% Asn: 0 0 13 0 7 7 0 7 13 0 0 0 0 0 7 % N
% Pro: 13 13 32 13 32 0 38 7 0 0 0 7 0 32 38 % P
% Gln: 0 0 0 0 0 19 0 0 0 7 0 0 13 25 0 % Q
% Arg: 7 13 0 0 0 7 0 0 7 7 7 0 7 0 0 % R
% Ser: 13 38 0 13 13 13 13 32 7 19 13 19 19 7 13 % S
% Thr: 0 7 7 7 0 0 7 7 0 7 0 32 0 0 0 % T
% Val: 13 7 0 7 0 0 0 0 0 0 0 0 0 7 13 % V
% Trp: 0 0 7 0 0 7 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _