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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHAF1B All Species: 6.97
Human Site: T453 Identified Species: 10.22
UniProt: Q13112 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13112 NP_005432.1 559 61493 T453 I R D P P S I T P A V K S P L
Chimpanzee Pan troglodytes XP_525468 559 61460 T453 I R D P P S I T P A V K S P L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544875 668 72082 R563 C T P P P Q A R P P P A P A A
Cat Felis silvestris
Mouse Mus musculus Q9D0N7 572 63114 I460 I K D S P S A I P A G K S P L
Rat Rattus norvegicus NP_001019912 572 62715 I460 I K D S P S A I P A G K S P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512498 575 62833 G461 E P S S T P P G G R S S A T P
Chicken Gallus gallus Q5R1S9 566 62559 S460 G I K N V P V S S S E E R K I
Frog Xenopus laevis Q8QFR2 1013 112021 Q620 E K I P A S K Q L S K R K G E
Zebra Danio Brachydanio rerio NP_998177 236 26626 D132 T L R G H I E D V Y D I S W T
Tiger Blowfish Takifugu rubipres O42611 1025 111838 K539 A K V L E D N K D G V K S C L
Fruit Fly Dros. melanogaster NP_610589 747 83376 I507 T A P M P I A I R R A P R K P
Honey Bee Apis mellifera XP_624307 452 51453 H348 I A V I S N I H Y T R L T D V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001191151 639 69080 T491 A P R R I Q L T T L S S P P S
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001132835 506 55177 D402 T K K P V C A D S M K V D N S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_974991 487 54088 V383 G E A V S I S V G K K P V D G
Baker's Yeast Sacchar. cerevisiae Q04199 468 51234 P364 Y D T D V L E P L C V V G N I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 73.8 N.A. 82.3 82.6 N.A. 75.6 72.7 20.9 33.6 20.6 35.7 38.6 N.A. 44.1
Protein Similarity: 100 99.8 N.A. 76.3 N.A. 88.4 88.4 N.A. 82 81.4 33 38.4 31.7 49.6 56.1 N.A. 58.2
P-Site Identity: 100 100 N.A. 20 N.A. 66.6 66.6 N.A. 0 0 13.3 6.6 26.6 6.6 13.3 N.A. 13.3
P-Site Similarity: 100 100 N.A. 20 N.A. 73.3 73.3 N.A. 6.6 33.3 33.3 6.6 33.3 6.6 33.3 N.A. 20
Percent
Protein Identity: N.A. 37.2 N.A. 35.6 25.7 N.A.
Protein Similarity: N.A. 53.1 N.A. 54.3 42.9 N.A.
P-Site Identity: N.A. 6.6 N.A. 0 6.6 N.A.
P-Site Similarity: N.A. 13.3 N.A. 0 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 13 7 0 7 0 32 0 0 25 7 7 7 7 7 % A
% Cys: 7 0 0 0 0 7 0 0 0 7 0 0 0 7 0 % C
% Asp: 0 7 25 7 0 7 0 13 7 0 7 0 7 13 0 % D
% Glu: 13 7 0 0 7 0 13 0 0 0 7 7 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 13 0 0 7 0 0 0 7 13 7 13 0 7 7 7 % G
% His: 0 0 0 0 7 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 32 7 7 7 7 19 19 19 0 0 0 7 0 0 13 % I
% Lys: 0 32 13 0 0 0 7 7 0 7 19 32 7 13 0 % K
% Leu: 0 7 0 7 0 7 7 0 13 7 0 7 0 0 32 % L
% Met: 0 0 0 7 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 7 7 0 0 0 0 0 0 13 0 % N
% Pro: 0 13 13 32 38 13 7 7 32 7 7 13 13 32 13 % P
% Gln: 0 0 0 0 0 13 0 7 0 0 0 0 0 0 0 % Q
% Arg: 0 13 13 7 0 0 0 7 7 13 7 7 13 0 0 % R
% Ser: 0 0 7 19 13 32 7 7 13 13 13 13 38 0 13 % S
% Thr: 19 7 7 0 7 0 0 19 7 7 0 0 7 7 7 % T
% Val: 0 0 13 7 19 0 7 7 7 0 25 13 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 7 0 0 0 0 0 0 0 7 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _