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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHAF1B All Species: 18.79
Human Site: T468 Identified Species: 27.56
UniProt: Q13112 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13112 NP_005432.1 559 61493 T468 P G P S E E K T L Q P S S Q N
Chimpanzee Pan troglodytes XP_525468 559 61460 T468 P G P S E E K T L Q P S S Q N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544875 668 72082 L578 H S E E K A A L Q P S T Q N P
Cat Felis silvestris
Mouse Mus musculus Q9D0N7 572 63114 T475 P Q P S E E K T L Q P A G Q N
Rat Rattus norvegicus NP_001019912 572 62715 T475 P R P S E E K T L Q P A A Q N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512498 575 62833 P476 P S E E R R D P Q P G G G H P
Chicken Gallus gallus Q5R1S9 566 62559 T475 S Q P A S Q S T K V N Q P R R
Frog Xenopus laevis Q8QFR2 1013 112021 K635 A D A D L A E K R K K G R P R
Zebra Danio Brachydanio rerio NP_998177 236 26626 S147 S D G N F M A S G S V D N T A
Tiger Blowfish Takifugu rubipres O42611 1025 111838 I554 L L T S A S K I E P M K A L D
Fruit Fly Dros. melanogaster NP_610589 747 83376 S522 E D K G N S E S S K P K D E M
Honey Bee Apis mellifera XP_624307 452 51453 I363 A W S D D G R I L I A S S T D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001191151 639 69080 S506 N Q P T N S S S S P P S S S S
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001132835 506 55177 A417 A N K L K M E A S P V A V G V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_974991 487 54088 E398 E E K K H D L E K G D E L M T
Baker's Yeast Sacchar. cerevisiae Q04199 468 51234 L379 H Y S P I T D L A W S E D G S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 73.8 N.A. 82.3 82.6 N.A. 75.6 72.7 20.9 33.6 20.6 35.7 38.6 N.A. 44.1
Protein Similarity: 100 99.8 N.A. 76.3 N.A. 88.4 88.4 N.A. 82 81.4 33 38.4 31.7 49.6 56.1 N.A. 58.2
P-Site Identity: 100 100 N.A. 0 N.A. 80 80 N.A. 6.6 13.3 0 0 13.3 6.6 20 N.A. 26.6
P-Site Similarity: 100 100 N.A. 13.3 N.A. 86.6 93.3 N.A. 6.6 33.3 13.3 20 26.6 33.3 40 N.A. 46.6
Percent
Protein Identity: N.A. 37.2 N.A. 35.6 25.7 N.A.
Protein Similarity: N.A. 53.1 N.A. 54.3 42.9 N.A.
P-Site Identity: N.A. 0 N.A. 0 0 N.A.
P-Site Similarity: N.A. 20 N.A. 6.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 7 7 7 13 13 7 7 0 7 19 13 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 0 13 7 7 13 0 0 0 7 7 13 0 13 % D
% Glu: 13 7 13 13 25 25 19 7 7 0 0 13 0 7 0 % E
% Phe: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 13 7 7 0 7 0 0 7 7 7 13 13 13 0 % G
% His: 13 0 0 0 7 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 0 0 7 0 0 13 0 7 0 0 0 0 0 % I
% Lys: 0 0 19 7 13 0 32 7 13 13 7 13 0 0 0 % K
% Leu: 7 7 0 7 7 0 7 13 32 0 0 0 7 7 0 % L
% Met: 0 0 0 0 0 13 0 0 0 0 7 0 0 7 7 % M
% Asn: 7 7 0 7 13 0 0 0 0 0 7 0 7 7 25 % N
% Pro: 32 0 38 7 0 0 0 7 0 32 38 0 7 7 13 % P
% Gln: 0 19 0 0 0 7 0 0 13 25 0 7 7 25 0 % Q
% Arg: 0 7 0 0 7 7 7 0 7 0 0 0 7 7 13 % R
% Ser: 13 13 13 32 7 19 13 19 19 7 13 25 25 7 13 % S
% Thr: 0 0 7 7 0 7 0 32 0 0 0 7 0 13 7 % T
% Val: 0 0 0 0 0 0 0 0 0 7 13 0 7 0 7 % V
% Trp: 0 7 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _