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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHAF1B All Species: 13.94
Human Site: T503 Identified Species: 20.44
UniProt: Q13112 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13112 NP_005432.1 559 61493 T503 T P R R I N L T P L K T D T P
Chimpanzee Pan troglodytes XP_525468 559 61460 T503 T P R R I N L T P L K T D T P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544875 668 72082 P613 P R R I N L I P L K T D T P P
Cat Felis silvestris
Mouse Mus musculus Q9D0N7 572 63114 T510 A P R R I N L T P L K T D T V
Rat Rattus norvegicus NP_001019912 572 62715 T510 A P R R I N L T P L R A D T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512498 575 62833 M511 T P R R I S L M P L K P D P P
Chicken Gallus gallus Q5R1S9 566 62559 S510 L K P D T P A S V Y T D T V P
Frog Xenopus laevis Q8QFR2 1013 112021 V670 S E K E L T C V T T S S L T L
Zebra Danio Brachydanio rerio NP_998177 236 26626 P182 V Q G V A W D P L G Q Y I S T
Tiger Blowfish Takifugu rubipres O42611 1025 111838 R589 T G L T P S E R P K E S T P M
Fruit Fly Dros. melanogaster NP_610589 747 83376 P557 K V S T E A V P P A E T S Q P
Honey Bee Apis mellifera XP_624307 452 51453 D398 S D I P I K S D I Y N E E S T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001191151 639 69080 Q541 T T D T P S N Q R P S Q N G G
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001132835 506 55177 P452 V T C E N K E P V T I D S M E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_974991 487 54088 T433 Q P L P S K I T T D G K E K E
Baker's Yeast Sacchar. cerevisiae Q04199 468 51234 P414 Q F G S R I E P P A M H A E P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 73.8 N.A. 82.3 82.6 N.A. 75.6 72.7 20.9 33.6 20.6 35.7 38.6 N.A. 44.1
Protein Similarity: 100 99.8 N.A. 76.3 N.A. 88.4 88.4 N.A. 82 81.4 33 38.4 31.7 49.6 56.1 N.A. 58.2
P-Site Identity: 100 100 N.A. 13.3 N.A. 86.6 73.3 N.A. 73.3 6.6 6.6 0 13.3 20 6.6 N.A. 6.6
P-Site Similarity: 100 100 N.A. 20 N.A. 86.6 80 N.A. 80 13.3 33.3 13.3 33.3 33.3 26.6 N.A. 20
Percent
Protein Identity: N.A. 37.2 N.A. 35.6 25.7 N.A.
Protein Similarity: N.A. 53.1 N.A. 54.3 42.9 N.A.
P-Site Identity: N.A. 0 N.A. 13.3 13.3 N.A.
P-Site Similarity: N.A. 0 N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 0 7 7 7 0 0 13 0 7 7 0 7 % A
% Cys: 0 0 7 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 7 0 0 7 7 0 7 0 19 32 0 0 % D
% Glu: 0 7 0 13 7 0 19 0 0 0 13 7 13 7 13 % E
% Phe: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 13 0 0 0 0 0 0 7 7 0 0 7 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 0 7 7 38 7 13 0 7 0 7 0 7 0 0 % I
% Lys: 7 7 7 0 0 19 0 0 0 13 25 7 0 7 0 % K
% Leu: 7 0 13 0 7 7 32 0 13 32 0 0 7 0 7 % L
% Met: 0 0 0 0 0 0 0 7 0 0 7 0 0 7 7 % M
% Asn: 0 0 0 0 13 25 7 0 0 0 7 0 7 0 0 % N
% Pro: 7 38 7 13 13 7 0 32 50 7 0 7 0 19 44 % P
% Gln: 13 7 0 0 0 0 0 7 0 0 7 7 0 7 0 % Q
% Arg: 0 7 38 32 7 0 0 7 7 0 7 0 0 0 0 % R
% Ser: 13 0 7 7 7 19 7 7 0 0 13 13 13 13 0 % S
% Thr: 32 13 0 19 7 7 0 32 13 13 13 25 19 32 13 % T
% Val: 13 7 0 7 0 0 7 7 13 0 0 0 0 7 7 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 13 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _