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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHAF1B All Species: 30.61
Human Site: Y346 Identified Species: 44.89
UniProt: Q13112 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13112 NP_005432.1 559 61493 Y346 G Y V S N I H Y H T L S D I S
Chimpanzee Pan troglodytes XP_525468 559 61460 Y346 G Y V S N I H Y H T L S D I S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544875 668 72082 F461 L Y D T Q Q P F P F G Y V S N
Cat Felis silvestris
Mouse Mus musculus Q9D0N7 572 63114 Y353 G Y V S N I H Y H T L S D I S
Rat Rattus norvegicus NP_001019912 572 62715 Y353 G Y V S N I H Y H T L S D I S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512498 575 62833 Y352 G Y V S N I H Y H T L S D I S
Chicken Gallus gallus Q5R1S9 566 62559 Y353 G Y V S N I H Y H T L S D I S
Frog Xenopus laevis Q8QFR2 1013 112021 G435 N M A S M M N G E S L E D I R
Zebra Danio Brachydanio rerio NP_998177 236 26626 Q30 Q S G D G K T Q R L A T A G V
Tiger Blowfish Takifugu rubipres O42611 1025 111838 Q376 E E K N S I H Q N I Y G K S L
Fruit Fly Dros. melanogaster NP_610589 747 83376 Y355 A I V S N I H Y S R L T D L A
Honey Bee Apis mellifera XP_624307 452 51453 I246 F R R L T F S I D G S L L I V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001191151 639 69080 Y345 G L I S N I H Y H Q L S D V T
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001132835 506 55177 N300 L F K P R G S N S D G F F K L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_974991 487 54088 S281 A L Q L P G A S K P V V V V R
Baker's Yeast Sacchar. cerevisiae Q04199 468 51234 R262 T L P S F F R R C S I S P C G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 73.8 N.A. 82.3 82.6 N.A. 75.6 72.7 20.9 33.6 20.6 35.7 38.6 N.A. 44.1
Protein Similarity: 100 99.8 N.A. 76.3 N.A. 88.4 88.4 N.A. 82 81.4 33 38.4 31.7 49.6 56.1 N.A. 58.2
P-Site Identity: 100 100 N.A. 6.6 N.A. 100 100 N.A. 100 100 26.6 0 13.3 53.3 6.6 N.A. 66.6
P-Site Similarity: 100 100 N.A. 26.6 N.A. 100 100 N.A. 100 100 46.6 6.6 33.3 73.3 6.6 N.A. 86.6
Percent
Protein Identity: N.A. 37.2 N.A. 35.6 25.7 N.A.
Protein Similarity: N.A. 53.1 N.A. 54.3 42.9 N.A.
P-Site Identity: N.A. 0 N.A. 0 13.3 N.A.
P-Site Similarity: N.A. 6.6 N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 7 0 0 0 7 0 0 0 7 0 7 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 0 0 7 0 % C
% Asp: 0 0 7 7 0 0 0 0 7 7 0 0 57 0 0 % D
% Glu: 7 7 0 0 0 0 0 0 7 0 0 7 0 0 0 % E
% Phe: 7 7 0 0 7 13 0 7 0 7 0 7 7 0 0 % F
% Gly: 44 0 7 0 7 13 0 7 0 7 13 7 0 7 7 % G
% His: 0 0 0 0 0 0 57 0 44 0 0 0 0 0 0 % H
% Ile: 0 7 7 0 0 57 0 7 0 7 7 0 0 50 0 % I
% Lys: 0 0 13 0 0 7 0 0 7 0 0 0 7 7 0 % K
% Leu: 13 19 0 13 0 0 0 0 0 7 57 7 7 7 13 % L
% Met: 0 7 0 0 7 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 7 50 0 7 7 7 0 0 0 0 0 7 % N
% Pro: 0 0 7 7 7 0 7 0 7 7 0 0 7 0 0 % P
% Gln: 7 0 7 0 7 7 0 13 0 7 0 0 0 0 0 % Q
% Arg: 0 7 7 0 7 0 7 7 7 7 0 0 0 0 13 % R
% Ser: 0 7 0 63 7 0 13 7 13 13 7 50 0 13 38 % S
% Thr: 7 0 0 7 7 0 7 0 0 38 0 13 0 0 7 % T
% Val: 0 0 44 0 0 0 0 0 0 0 7 7 13 13 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 44 0 0 0 0 0 50 0 0 7 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _