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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP4
All Species:
22.73
Human Site:
S82
Identified Species:
62.5
UniProt:
Q13115
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13115
NP_001385.1
394
42953
S82
R
R
A
K
G
S
V
S
L
E
Q
I
L
P
A
Chimpanzee
Pan troglodytes
XP_520046
394
42978
S82
R
R
A
K
G
S
V
S
L
E
Q
I
L
P
A
Rhesus Macaque
Macaca mulatta
XP_001110903
394
42978
S82
R
R
A
K
G
S
V
S
L
E
Q
I
L
P
A
Dog
Lupus familis
XP_539995
477
50926
S165
R
R
A
K
G
S
V
S
L
E
Q
I
L
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFV3
398
43353
S86
R
R
A
K
G
S
V
S
L
E
Q
I
L
P
A
Rat
Rattus norvegicus
Q62767
395
43169
S83
R
R
A
K
G
S
V
S
L
E
Q
I
L
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PW71
375
41034
R78
L
P
A
E
G
E
V
R
A
R
L
R
A
G
L
Frog
Xenopus laevis
NP_001080570
369
40246
Q72
H
I
V
P
N
E
E
Q
R
C
R
L
V
A
G
Zebra Danio
Brachydanio rerio
XP_001923945
367
40502
G70
S
L
D
Q
I
L
S
G
D
D
E
A
R
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.2
78.4
N.A.
95.9
96.1
N.A.
N.A.
81.7
61.4
68.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
99.2
79.6
N.A.
96.4
96.7
N.A.
N.A.
89
74.6
80.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
20
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
26.6
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
78
0
0
0
0
0
12
0
0
12
12
12
67
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
0
0
12
12
0
0
0
0
0
% D
% Glu:
0
0
0
12
0
23
12
0
0
67
12
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
78
0
0
12
0
0
0
0
0
12
12
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
12
0
0
0
0
0
0
67
0
0
0
% I
% Lys:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
12
12
0
0
0
12
0
0
67
0
12
12
67
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
12
0
0
0
0
0
0
0
0
0
67
0
% P
% Gln:
0
0
0
12
0
0
0
12
0
0
67
0
0
0
0
% Q
% Arg:
67
67
0
0
0
0
0
12
12
12
12
12
12
0
12
% R
% Ser:
12
0
0
0
0
67
12
67
0
0
0
0
0
12
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
12
0
0
0
78
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _