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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MTAP All Species: 22.42
Human Site: T188 Identified Species: 44.85
UniProt: Q13126 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13126 NP_002442.2 283 31236 T188 A E S F M F R T W G A D V I N
Chimpanzee Pan troglodytes XP_001152954 300 33333 T188 A E S F M F R T W G A D V I N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531959 366 40169 T271 A E S F M F R T W G A D V I N
Cat Felis silvestris
Mouse Mus musculus Q9CQ65 283 31043 T188 A E S L I F R T W G A D V V N
Rat Rattus norvegicus P85973 289 32283 S195 Q E G T Y I M S A G P T F E T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026775 280 30830 S185 A E S L M F R S W G A D V I N
Frog Xenopus laevis NP_001090018 251 27877 L156 A E S H M F R L W G A D V I N
Zebra Danio Brachydanio rerio NP_956848 280 30829 Q185 A E S L M F R Q W G A D V I N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V813 289 31999 Q194 S E S H M F R Q W G G D L I N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09438 288 31546 S180 A E S M V F K S W G A S L V N
Sea Urchin Strong. purpuratus XP_785380 254 27972 N160 I L G G D V I N M T T V P E V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q07938 337 37838 M222 A E S K M Y R M F G G H V I N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 N.A. 75.1 N.A. 93.6 24.9 N.A. N.A. 82.6 69.2 78.8 N.A. 57 N.A. 47.5 53
Protein Similarity: 100 94.3 N.A. 75.9 N.A. 96.8 43.9 N.A. N.A. 89.7 77 89 N.A. 71.6 N.A. 64.2 67.1
P-Site Identity: 100 100 N.A. 100 N.A. 80 13.3 N.A. N.A. 86.6 86.6 86.6 N.A. 66.6 N.A. 53.3 0
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 20 N.A. N.A. 93.3 86.6 86.6 N.A. 80 N.A. 86.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 47.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 60 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 75 0 0 0 0 0 0 0 9 0 67 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 0 0 0 0 67 0 0 0 % D
% Glu: 0 92 0 0 0 0 0 0 0 0 0 0 0 17 0 % E
% Phe: 0 0 0 25 0 75 0 0 9 0 0 0 9 0 0 % F
% Gly: 0 0 17 9 0 0 0 0 0 92 17 0 0 0 0 % G
% His: 0 0 0 17 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 9 0 0 0 9 9 9 0 0 0 0 0 0 67 0 % I
% Lys: 0 0 0 9 0 0 9 0 0 0 0 0 0 0 0 % K
% Leu: 0 9 0 25 0 0 0 9 0 0 0 0 17 0 0 % L
% Met: 0 0 0 9 67 0 9 9 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 84 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 9 0 9 0 0 % P
% Gln: 9 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 75 0 0 0 0 0 0 0 0 % R
% Ser: 9 0 84 0 0 0 0 25 0 0 0 9 0 0 0 % S
% Thr: 0 0 0 9 0 0 0 34 0 9 9 9 0 0 9 % T
% Val: 0 0 0 0 9 9 0 0 0 0 0 9 67 17 9 % V
% Trp: 0 0 0 0 0 0 0 0 75 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _