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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTAP
All Species:
37.58
Human Site:
Y221
Identified Species:
75.15
UniProt:
Q13126
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13126
NP_002442.2
283
31236
Y221
S
I
A
M
A
T
D
Y
D
C
W
K
E
H
E
Chimpanzee
Pan troglodytes
XP_001152954
300
33333
Y221
S
I
A
M
A
T
D
Y
D
C
W
K
E
H
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531959
366
40169
Y304
S
I
A
M
A
T
D
Y
D
C
W
K
E
H
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQ65
283
31043
Y221
S
I
A
M
A
T
D
Y
D
C
W
K
E
H
E
Rat
Rattus norvegicus
P85973
289
32283
A228
T
V
P
E
V
I
V
A
R
H
C
G
L
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026775
280
30830
Y218
S
I
A
M
A
T
D
Y
D
C
W
K
E
H
E
Frog
Xenopus laevis
NP_001090018
251
27877
Y189
S
I
A
M
A
T
D
Y
D
C
W
K
E
H
E
Zebra Danio
Brachydanio rerio
NP_956848
280
30829
Y218
S
I
A
M
A
T
D
Y
D
C
W
K
E
H
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V813
289
31999
Y227
S
V
A
I
A
T
D
Y
D
C
W
R
M
G
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09438
288
31546
Y213
T
T
A
L
V
T
D
Y
D
C
W
K
E
E
D
Sea Urchin
Strong. purpuratus
XP_785380
254
27972
E193
Y
D
S
W
R
E
S
E
E
S
V
S
G
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07938
337
37838
Y255
M
I
C
M
S
T
D
Y
D
A
W
R
D
E
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.3
N.A.
75.1
N.A.
93.6
24.9
N.A.
N.A.
82.6
69.2
78.8
N.A.
57
N.A.
47.5
53
Protein Similarity:
100
94.3
N.A.
75.9
N.A.
96.8
43.9
N.A.
N.A.
89.7
77
89
N.A.
71.6
N.A.
64.2
67.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
N.A.
100
100
100
N.A.
60
N.A.
60
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
N.A.
100
100
100
N.A.
80
N.A.
80
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
75
0
67
0
0
9
0
9
0
0
0
0
9
% A
% Cys:
0
0
9
0
0
0
0
0
0
75
9
0
0
0
9
% C
% Asp:
0
9
0
0
0
0
84
0
84
0
0
0
9
0
9
% D
% Glu:
0
0
0
9
0
9
0
9
9
0
0
0
67
25
59
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
9
9
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
59
0
% H
% Ile:
0
67
0
9
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
67
0
0
0
% K
% Leu:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% L
% Met:
9
0
0
67
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
9
0
0
17
0
9
0
% R
% Ser:
67
0
9
0
9
0
9
0
0
9
0
9
0
0
9
% S
% Thr:
17
9
0
0
0
84
0
0
0
0
0
0
0
0
0
% T
% Val:
0
17
0
0
17
0
9
0
0
0
9
0
0
0
9
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
84
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _