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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKAA1 All Species: 32.73
Human Site: S176 Identified Species: 60
UniProt: Q13131 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13131 NP_006242.5 559 64009 S176 F G L S N M M S D G E F L R T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086285 574 65620 S191 F G L S N M M S D G E F L R T
Dog Lupus familis XP_536491 563 64691 S180 F G L S N M M S D G E F L R T
Cat Felis silvestris
Mouse Mus musculus Q5EG47 559 63911 S176 F G L S N M M S D G E F L R T
Rat Rattus norvegicus P54645 559 63955 S176 F G L S N M M S D G E F L R T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506315 519 59478 S147 F L R T S C G S P N Y A A P E
Chicken Gallus gallus Q9IA88 798 88848 K174 F G F G N F Y K S G E P L S T
Frog Xenopus laevis NP_001083882 560 64031 A176 F G L S N M M A D G E F L R T
Zebra Danio Brachydanio rerio NP_001103756 573 65002 S166 F G L S N M M S D G E F L R T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623371 515 58559 D151 K P E N L L L D H N L H V K I
Nematode Worm Caenorhab. elegans Q95ZQ4 626 70425 T236 F G L S N I M T D G D F L R T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38997 535 61163 L166 N M V V H R D L K P E N L L L
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 T203 F G L S N I M T D G N F L K T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.2 92.5 N.A. 98.7 99.1 N.A. 89.2 27 88.7 84.4 N.A. N.A. 62.2 53.5 N.A.
Protein Similarity: 100 N.A. 97.3 93.7 N.A. 99.4 99.6 N.A. 91 43.1 94.6 90.9 N.A. N.A. 75.1 66.4 N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 13.3 46.6 93.3 100 N.A. N.A. 0 80 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 26.6 46.6 100 100 N.A. N.A. 33.3 100 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 45 33.4 N.A.
Protein Similarity: N.A. N.A. N.A. 62.4 51.9 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 73.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 93.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 0 0 8 8 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 8 70 0 8 0 0 0 0 % D
% Glu: 0 0 8 0 0 0 0 0 0 0 70 0 0 0 8 % E
% Phe: 85 0 8 0 0 8 0 0 0 0 0 70 0 0 0 % F
% Gly: 0 77 0 8 0 0 8 0 0 77 0 0 0 0 0 % G
% His: 0 0 0 0 8 0 0 0 8 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 16 0 0 0 0 0 0 0 0 8 % I
% Lys: 8 0 0 0 0 0 0 8 8 0 0 0 0 16 0 % K
% Leu: 0 8 70 0 8 8 8 8 0 0 8 0 85 8 8 % L
% Met: 0 8 0 0 0 54 70 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 8 77 0 0 0 0 16 8 8 0 0 0 % N
% Pro: 0 8 0 0 0 0 0 0 8 8 0 8 0 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 8 0 0 0 0 0 0 0 62 0 % R
% Ser: 0 0 0 70 8 0 0 54 8 0 0 0 0 8 0 % S
% Thr: 0 0 0 8 0 0 0 16 0 0 0 0 0 0 77 % T
% Val: 0 0 8 8 0 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _