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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA1
All Species:
22.73
Human Site:
S251
Identified Species:
41.67
UniProt:
Q13131
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13131
NP_006242.5
559
64009
S251
T
P
Q
Y
L
N
P
S
V
I
S
L
L
K
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086285
574
65620
S266
T
P
Q
Y
L
N
P
S
V
I
S
L
L
K
H
Dog
Lupus familis
XP_536491
563
64691
S255
T
P
Q
Y
L
N
P
S
V
I
S
L
L
K
H
Cat
Felis silvestris
Mouse
Mus musculus
Q5EG47
559
63911
S251
T
P
Q
Y
L
N
P
S
V
I
S
L
L
K
H
Rat
Rattus norvegicus
P54645
559
63955
S251
T
P
Q
Y
L
N
P
S
V
I
S
L
L
K
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
V222
L
L
K
H
M
L
Q
V
D
P
M
K
R
A
T
Chicken
Gallus gallus
Q9IA88
798
88848
D249
I
P
Y
F
M
S
E
D
C
E
T
L
I
R
R
Frog
Xenopus laevis
NP_001083882
560
64031
P251
T
P
Q
Y
L
N
P
P
V
I
S
L
L
K
H
Zebra Danio
Brachydanio rerio
NP_001103756
573
65002
S241
T
P
Q
Y
L
N
P
S
V
I
S
L
L
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
F226
D
E
H
V
P
T
L
F
R
K
I
K
S
G
V
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
P311
T
P
D
F
L
E
R
P
I
V
N
L
L
H
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
D241
L
C
G
T
L
P
F
D
D
E
N
I
P
N
L
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
G278
L
P
K
F
L
S
P
G
A
A
G
L
I
K
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.2
92.5
N.A.
98.7
99.1
N.A.
89.2
27
88.7
84.4
N.A.
N.A.
62.2
53.5
N.A.
Protein Similarity:
100
N.A.
97.3
93.7
N.A.
99.4
99.6
N.A.
91
43.1
94.6
90.9
N.A.
N.A.
75.1
66.4
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
13.3
93.3
100
N.A.
N.A.
0
40
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
20
53.3
93.3
100
N.A.
N.A.
0
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
45
33.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.4
51.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
8
0
0
0
8
0
% A
% Cys:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
0
0
16
16
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
8
8
0
0
16
0
0
0
0
0
% E
% Phe:
0
0
0
24
0
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
8
0
0
8
0
0
8
0
% G
% His:
0
0
8
8
0
0
0
0
0
0
0
0
0
8
62
% H
% Ile:
8
0
0
0
0
0
0
0
8
54
8
8
16
0
0
% I
% Lys:
0
0
16
0
0
0
0
0
0
8
0
16
0
62
0
% K
% Leu:
24
8
0
0
77
8
8
0
0
0
0
77
62
0
8
% L
% Met:
0
0
0
0
16
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
54
0
0
0
0
16
0
0
8
0
% N
% Pro:
0
77
0
0
8
8
62
16
0
8
0
0
8
0
0
% P
% Gln:
0
0
54
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
8
0
0
0
8
8
16
% R
% Ser:
0
0
0
0
0
16
0
47
0
0
54
0
8
0
0
% S
% Thr:
62
0
0
8
0
8
0
0
0
0
8
0
0
0
8
% T
% Val:
0
0
0
8
0
0
0
8
54
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
54
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _