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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA1
All Species:
27.88
Human Site:
T482
Identified Species:
51.11
UniProt:
Q13131
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13131
NP_006242.5
559
64009
T482
R
S
I
D
D
E
I
T
E
A
K
S
G
T
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086285
574
65620
T497
R
S
I
D
D
E
I
T
E
A
K
S
G
T
A
Dog
Lupus familis
XP_536491
563
64691
T486
R
S
I
D
D
E
I
T
E
A
K
S
G
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q5EG47
559
63911
T482
R
S
I
D
D
E
I
T
E
A
K
S
G
T
A
Rat
Rattus norvegicus
P54645
559
63955
T482
R
S
I
D
D
E
I
T
E
A
K
S
G
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
T449
I
E
A
K
S
G
T
T
T
P
Q
R
S
G
S
Chicken
Gallus gallus
Q9IA88
798
88848
N649
G
S
S
R
E
G
R
N
L
L
E
E
V
L
Q
Frog
Xenopus laevis
NP_001083882
560
64031
T483
R
S
I
D
D
E
V
T
E
S
K
S
E
S
A
Zebra Danio
Brachydanio rerio
NP_001103756
573
65002
M476
R
S
I
D
D
D
M
M
E
V
K
S
G
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
K447
Y
S
V
R
V
R
Q
K
N
K
L
T
D
R
Y
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
S541
K
S
L
A
D
E
E
S
G
S
A
S
A
S
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
S465
S
S
A
D
G
M
L
S
N
S
M
H
D
N
N
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
P563
T
N
T
N
E
K
I
P
D
L
M
K
M
V
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.2
92.5
N.A.
98.7
99.1
N.A.
89.2
27
88.7
84.4
N.A.
N.A.
62.2
53.5
N.A.
Protein Similarity:
100
N.A.
97.3
93.7
N.A.
99.4
99.6
N.A.
91
43.1
94.6
90.9
N.A.
N.A.
75.1
66.4
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
6.6
73.3
73.3
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
20
20
93.3
86.6
N.A.
N.A.
20
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
45
33.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.4
51.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
8
0
0
0
0
0
39
8
0
8
0
54
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
62
62
8
0
0
8
0
0
0
16
0
0
% D
% Glu:
0
8
0
0
16
54
8
0
54
0
8
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
16
0
0
8
0
0
0
47
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
8
0
54
0
0
0
47
0
0
0
0
0
0
0
8
% I
% Lys:
8
0
0
8
0
8
0
8
0
8
54
8
0
0
0
% K
% Leu:
0
0
8
0
0
0
8
0
8
16
8
0
0
8
0
% L
% Met:
0
0
0
0
0
8
8
8
0
0
16
0
8
0
0
% M
% Asn:
0
8
0
8
0
0
0
8
16
0
0
0
0
8
8
% N
% Pro:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
8
% Q
% Arg:
54
0
0
16
0
8
8
0
0
0
0
8
0
8
0
% R
% Ser:
8
85
8
0
8
0
0
16
0
24
0
62
8
16
16
% S
% Thr:
8
0
8
0
0
0
8
54
8
0
0
8
0
47
0
% T
% Val:
0
0
8
0
8
0
8
0
0
8
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _