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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA1
All Species:
27.27
Human Site:
Y441
Identified Species:
50
UniProt:
Q13131
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13131
NP_006242.5
559
64009
Y441
E
W
K
V
V
N
P
Y
Y
L
R
V
R
R
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086285
574
65620
Y456
E
W
K
V
V
N
P
Y
Y
L
R
V
R
R
K
Dog
Lupus familis
XP_536491
563
64691
Y445
E
W
K
V
V
N
P
Y
Y
L
R
V
R
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5EG47
559
63911
Y441
E
W
K
V
V
N
P
Y
Y
L
R
V
R
R
K
Rat
Rattus norvegicus
P54645
559
63955
Y441
E
W
K
V
V
N
P
Y
Y
L
R
V
R
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
K408
Y
Y
L
R
V
R
R
K
N
P
V
T
S
T
Y
Chicken
Gallus gallus
Q9IA88
798
88848
F608
G
L
N
K
I
K
G
F
A
R
Q
V
C
Q
S
Frog
Xenopus laevis
NP_001083882
560
64031
Y442
E
W
K
L
V
N
P
Y
Y
L
R
V
R
R
K
Zebra Danio
Brachydanio rerio
NP_001103756
573
65002
Y435
E
W
K
V
V
N
P
Y
Y
L
R
V
R
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
W406
T
P
I
K
R
A
K
W
H
L
G
I
R
S
Q
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
H500
W
K
V
L
N
P
Y
H
V
I
V
R
R
K
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
P424
G
L
Q
S
R
A
H
P
R
E
I
M
T
E
V
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
I522
P
L
D
V
M
G
E
I
Y
I
A
L
K
N
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.2
92.5
N.A.
98.7
99.1
N.A.
89.2
27
88.7
84.4
N.A.
N.A.
62.2
53.5
N.A.
Protein Similarity:
100
N.A.
97.3
93.7
N.A.
99.4
99.6
N.A.
91
43.1
94.6
90.9
N.A.
N.A.
75.1
66.4
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
6.6
93.3
100
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
33.3
100
100
N.A.
N.A.
40
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
45
33.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.4
51.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
0
0
8
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
54
0
0
0
0
0
8
0
0
8
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
16
0
0
0
0
8
8
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
8
8
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
8
0
16
8
8
0
0
0
% I
% Lys:
0
8
54
16
0
8
8
8
0
0
0
0
8
8
54
% K
% Leu:
0
24
8
16
0
0
0
0
0
62
0
8
0
0
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
8
54
0
0
8
0
0
0
0
8
0
% N
% Pro:
8
8
0
0
0
8
54
8
0
8
0
0
0
0
8
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
8
0
0
8
8
% Q
% Arg:
0
0
0
8
16
8
8
0
8
8
54
8
70
54
0
% R
% Ser:
0
0
0
8
0
0
0
0
0
0
0
0
8
8
8
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
8
8
8
0
% T
% Val:
0
0
8
54
62
0
0
0
8
0
16
62
0
0
8
% V
% Trp:
8
54
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
8
54
62
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _