KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR1H3
All Species:
26.67
Human Site:
S198
Identified Species:
45.13
UniProt:
Q13133
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13133
NP_001123573.1
447
50396
S198
S
L
P
P
R
A
S
S
P
P
Q
I
L
P
Q
Chimpanzee
Pan troglodytes
XP_001168389
511
57483
S198
S
L
P
P
R
A
S
S
P
P
Q
I
L
P
Q
Rhesus Macaque
Macaca mulatta
XP_001108843
447
50535
S198
S
L
P
P
R
A
S
S
P
P
Q
I
L
P
Q
Dog
Lupus familis
XP_540745
447
50216
S198
S
M
P
P
R
V
S
S
P
P
Q
V
L
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0Y9
445
50458
S196
S
V
S
P
R
V
S
S
P
P
Q
V
L
P
Q
Rat
Rattus norvegicus
Q62685
445
50536
S196
S
V
S
P
R
V
S
S
P
P
Q
V
L
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517956
624
68359
L375
P
P
P
P
Q
A
S
L
P
G
P
A
L
P
Q
Chicken
Gallus gallus
O42392
451
51281
S201
S
V
V
S
Q
D
F
S
S
E
D
S
N
D
V
Frog
Xenopus laevis
P51126
458
50544
Y178
K
P
E
A
I
E
S
Y
I
L
S
P
E
T
Q
Zebra Danio
Brachydanio rerio
Q9PTN2
453
50848
V189
F
V
R
F
R
P
P
V
R
E
G
P
V
T
R
Tiger Blowfish
Takifugu rubipres
Q9W5Z3
447
49514
Q178
V
L
S
P
D
T
E
Q
M
I
N
R
V
R
K
Fruit Fly
Dros. melanogaster
P34021
878
93835
T396
C
E
P
P
Q
H
A
T
I
P
L
L
P
D
E
Honey Bee
Apis mellifera
NP_001091685
629
66768
S352
T
M
N
G
S
P
G
S
G
G
I
R
S
D
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123279
490
55735
P224
I
H
K
E
L
E
I
P
G
P
E
D
L
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
97.7
92.1
N.A.
91.7
91.2
N.A.
61.8
24.1
31.6
25.1
32.2
23.3
30.3
N.A.
38.7
Protein Similarity:
100
87.4
98.4
94.1
N.A.
94.4
93.9
N.A.
65
40.1
47.1
45.7
50.1
33.7
45.9
N.A.
57.9
P-Site Identity:
100
100
100
80
N.A.
73.3
73.3
N.A.
53.3
13.3
13.3
6.6
13.3
20
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
60
26.6
13.3
26.6
26.6
53.3
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
29
8
0
0
0
0
8
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
8
0
0
0
0
8
8
0
22
0
% D
% Glu:
0
8
8
8
0
15
8
0
0
15
8
0
8
0
8
% E
% Phe:
8
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
8
0
15
15
8
0
0
0
0
% G
% His:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
8
0
15
8
8
22
0
0
0
% I
% Lys:
8
0
8
0
0
0
0
0
0
0
0
0
0
8
8
% K
% Leu:
0
29
0
0
8
0
0
8
0
8
8
8
58
0
0
% L
% Met:
0
15
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
8
0
8
0
0
% N
% Pro:
8
15
43
65
0
15
8
8
50
58
8
15
8
50
0
% P
% Gln:
0
0
0
0
22
0
0
8
0
0
43
0
0
0
65
% Q
% Arg:
0
0
8
0
50
0
0
0
8
0
0
15
0
8
15
% R
% Ser:
50
0
22
8
8
0
58
58
8
0
8
8
8
0
0
% S
% Thr:
8
0
0
0
0
8
0
8
0
0
0
0
0
15
0
% T
% Val:
8
29
8
0
0
22
0
8
0
0
0
22
15
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _