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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NR1H3 All Species: 27.27
Human Site: S413 Identified Species: 46.15
UniProt: Q13133 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.54
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13133 NP_001123573.1 447 50396 S413 R M L M K L V S L R T L S S V
Chimpanzee Pan troglodytes XP_001168389 511 57483 S477 R M L M K L V S L R T L S S V
Rhesus Macaque Macaca mulatta XP_001108843 447 50535 S413 R M L M K L V S L R T L S S V
Dog Lupus familis XP_540745 447 50216 S413 R M L M K L V S L R T L S S V
Cat Felis silvestris
Mouse Mus musculus Q9Z0Y9 445 50458 S411 R M L M K L V S L R T L S S V
Rat Rattus norvegicus Q62685 445 50536 S411 R M L M K L V S L R T L S S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517956 624 68359 S590 R M L M K L V S L R T L S S V
Chicken Gallus gallus O42392 451 51281 D413 K M I Q K L A D L R S L N E E
Frog Xenopus laevis P51126 458 50544 D383 K M L M K I T D L R T V S A K
Zebra Danio Brachydanio rerio Q9PTN2 453 50848 D415 K M I Q K L A D L R S L N E E
Tiger Blowfish Takifugu rubipres Q9W5Z3 447 49514 D375 K M L M K I T D L R S I S A K
Fruit Fly Dros. melanogaster P34021 878 93835 E620 K L L S I L T E L R T L G N Q
Honey Bee Apis mellifera NP_001091685 629 66768 E595 R L L S V L T E L R T L G N Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001123279 490 55735 E457 K V L M K L T E L R S L N N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.4 97.7 92.1 N.A. 91.7 91.2 N.A. 61.8 24.1 31.6 25.1 32.2 23.3 30.3 N.A. 38.7
Protein Similarity: 100 87.4 98.4 94.1 N.A. 94.4 93.9 N.A. 65 40.1 47.1 45.7 50.1 33.7 45.9 N.A. 57.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 40 53.3 40 46.6 40 46.6 N.A. 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 66.6 80 66.6 80 60 60 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 15 0 0 0 0 0 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 29 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 22 0 0 0 0 0 15 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 15 0 8 15 0 0 0 0 0 8 0 0 0 % I
% Lys: 43 0 0 0 86 0 0 0 0 0 0 0 0 0 15 % K
% Leu: 0 15 86 0 0 86 0 0 100 0 0 86 0 0 0 % L
% Met: 0 79 0 72 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 22 22 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 15 % Q
% Arg: 58 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % R
% Ser: 0 0 0 15 0 0 0 50 0 0 29 0 65 50 8 % S
% Thr: 0 0 0 0 0 0 36 0 0 0 72 0 0 0 0 % T
% Val: 0 8 0 0 8 0 50 0 0 0 0 8 0 0 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _