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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CALCOCO2
All Species:
16.36
Human Site:
S393
Identified Species:
40
UniProt:
Q13137
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13137
NP_005822.1
446
52254
S393
S
S
S
P
S
P
L
S
I
K
K
C
P
I
C
Chimpanzee
Pan troglodytes
XP_511940
446
52201
S393
S
S
S
P
S
P
L
S
I
K
K
C
P
I
C
Rhesus Macaque
Macaca mulatta
XP_001090780
446
52132
S393
S
S
S
P
S
Q
L
S
I
K
K
C
P
I
C
Dog
Lupus familis
XP_537667
449
52098
T393
S
S
A
P
S
L
R
T
M
K
R
C
P
T
C
Cat
Felis silvestris
Mouse
Mus musculus
A2A6M5
331
40118
A288
A
S
W
E
E
E
K
A
S
W
E
K
E
K
A
Rat
Rattus norvegicus
Q66HA4
813
93178
E682
D
G
A
F
Y
P
D
E
I
Q
R
P
P
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510062
824
94531
E690
D
G
A
F
Y
P
D
E
I
Q
R
P
P
T
R
Chicken
Gallus gallus
XP_418115
470
54625
S414
A
R
A
T
G
I
D
S
I
R
K
C
P
I
C
Frog
Xenopus laevis
Q6DD09
547
63016
S486
L
P
V
D
H
S
D
S
D
D
E
S
P
G
D
Zebra Danio
Brachydanio rerio
Q6P132
823
94492
A597
D
R
Y
K
S
Q
V
A
E
K
G
R
E
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.8
83.5
N.A.
37
25.9
N.A.
25.4
48.7
25
27.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
97.3
91.3
N.A.
51.7
38.8
N.A.
38.8
65.9
42.2
39.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
53.3
N.A.
6.6
20
N.A.
20
46.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
80
N.A.
26.6
46.6
N.A.
40
66.6
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
40
0
0
0
0
20
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
50
% C
% Asp:
30
0
0
10
0
0
40
0
10
10
0
0
0
0
10
% D
% Glu:
0
0
0
10
10
10
0
20
10
0
20
0
20
0
0
% E
% Phe:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
20
0
0
10
0
0
0
0
0
10
0
0
10
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
60
0
0
0
0
40
0
% I
% Lys:
0
0
0
10
0
0
10
0
0
50
40
10
0
10
10
% K
% Leu:
10
0
0
0
0
10
30
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
40
0
40
0
0
0
0
0
20
80
0
0
% P
% Gln:
0
0
0
0
0
20
0
0
0
20
0
0
0
0
0
% Q
% Arg:
0
20
0
0
0
0
10
0
0
10
30
10
0
0
20
% R
% Ser:
40
50
30
0
50
10
0
50
10
0
0
10
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
10
0
0
0
0
0
20
0
% T
% Val:
0
0
10
0
0
0
10
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
10
0
20
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _