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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TARDBP
All Species:
20.91
Human Site:
S144
Identified Species:
57.5
UniProt:
Q13148
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13148
NP_031401.1
414
44740
S144
K
D
L
K
T
G
H
S
K
G
F
G
F
V
R
Chimpanzee
Pan troglodytes
XP_001135126
357
37996
K102
K
V
K
R
A
V
Q
K
T
S
D
L
I
V
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q921F2
414
44529
S144
K
D
L
K
T
G
H
S
K
G
F
G
F
V
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515386
295
33249
G40
A
Q
F
P
G
A
C
G
L
R
Y
R
N
P
V
Chicken
Gallus gallus
Q5ZLN5
414
44571
S144
K
D
I
K
T
G
H
S
K
G
F
G
F
V
R
Frog
Xenopus laevis
Q6NU14
291
32937
M36
F
F
L
I
R
S
K
M
F
I
G
G
L
S
W
Zebra Danio
Brachydanio rerio
NP_958884
412
44409
S150
R
D
V
K
T
G
N
S
K
G
F
G
F
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392590
466
50438
S146
K
D
A
K
S
G
Q
S
K
G
F
G
F
I
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q99383
534
59631
S199
K
D
P
A
T
G
R
S
R
G
F
G
F
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
N.A.
N.A.
N.A.
96.1
N.A.
N.A.
66.6
95.1
22.7
76
N.A.
N.A.
49.5
N.A.
N.A.
Protein Similarity:
100
86.2
N.A.
N.A.
N.A.
98.7
N.A.
N.A.
69.5
97.3
38.4
86.4
N.A.
N.A.
63
N.A.
N.A.
P-Site Identity:
100
13.3
N.A.
N.A.
N.A.
100
N.A.
N.A.
0
93.3
13.3
80
N.A.
N.A.
73.3
N.A.
N.A.
P-Site Similarity:
100
20
N.A.
N.A.
N.A.
100
N.A.
N.A.
6.6
100
13.3
100
N.A.
N.A.
86.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
12
12
12
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
67
0
0
0
0
0
0
0
0
12
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
12
12
12
0
0
0
0
0
12
0
67
0
67
0
0
% F
% Gly:
0
0
0
0
12
67
0
12
0
67
12
78
0
0
0
% G
% His:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
12
0
0
0
0
0
12
0
0
12
12
0
% I
% Lys:
67
0
12
56
0
0
12
12
56
0
0
0
0
0
0
% K
% Leu:
0
0
34
0
0
0
0
0
12
0
0
12
12
12
12
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
0
0
12
0
0
% N
% Pro:
0
0
12
12
0
0
0
0
0
0
0
0
0
12
0
% P
% Gln:
0
12
0
0
0
0
23
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
12
12
0
12
0
12
12
0
12
0
0
56
% R
% Ser:
0
0
0
0
12
12
0
67
0
12
0
0
0
12
12
% S
% Thr:
0
0
0
0
56
0
0
0
12
0
0
0
0
0
0
% T
% Val:
0
12
12
0
0
12
0
0
0
0
0
0
0
56
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _