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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TARDBP
All Species:
20.91
Human Site:
Y123
Identified Species:
57.5
UniProt:
Q13148
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13148
NP_031401.1
414
44740
Y123
T
E
Q
D
L
K
E
Y
F
S
T
F
G
E
V
Chimpanzee
Pan troglodytes
XP_001135126
357
37996
N81
V
V
N
Y
P
K
D
N
K
R
K
M
D
E
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q921F2
414
44529
Y123
T
E
Q
D
L
K
D
Y
F
S
T
F
G
E
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515386
295
33249
P19
N
D
E
P
I
E
I
P
S
E
D
D
G
T
V
Chicken
Gallus gallus
Q5ZLN5
414
44571
Y123
T
E
Q
D
L
K
E
Y
F
S
T
F
G
E
V
Frog
Xenopus laevis
Q6NU14
291
32937
L15
R
S
T
L
V
S
T
L
S
R
L
L
R
R
H
Zebra Danio
Brachydanio rerio
NP_958884
412
44409
Y129
S
E
Q
D
L
K
D
Y
F
G
T
F
G
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392590
466
50438
Y125
T
E
Q
N
L
R
E
Y
F
E
T
F
G
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q99383
534
59631
Y178
T
E
D
N
L
R
E
Y
F
G
K
Y
G
T
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
N.A.
N.A.
N.A.
96.1
N.A.
N.A.
66.6
95.1
22.7
76
N.A.
N.A.
49.5
N.A.
N.A.
Protein Similarity:
100
86.2
N.A.
N.A.
N.A.
98.7
N.A.
N.A.
69.5
97.3
38.4
86.4
N.A.
N.A.
63
N.A.
N.A.
P-Site Identity:
100
13.3
N.A.
N.A.
N.A.
93.3
N.A.
N.A.
13.3
100
0
80
N.A.
N.A.
80
N.A.
N.A.
P-Site Similarity:
100
20
N.A.
N.A.
N.A.
100
N.A.
N.A.
40
100
6.6
93.3
N.A.
N.A.
93.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
12
45
0
0
34
0
0
0
12
12
12
0
0
% D
% Glu:
0
67
12
0
0
12
45
0
0
23
0
0
0
67
0
% E
% Phe:
0
0
0
0
0
0
0
0
67
0
0
56
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
23
0
0
78
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% H
% Ile:
0
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
56
0
0
12
0
23
0
0
0
0
% K
% Leu:
0
0
0
12
67
0
0
12
0
0
12
12
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
12
0
12
23
0
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
12
12
0
0
12
0
0
0
0
0
0
0
% P
% Gln:
0
0
56
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
23
0
0
0
23
0
0
12
12
0
% R
% Ser:
12
12
0
0
0
12
0
0
23
34
0
0
0
0
0
% S
% Thr:
56
0
12
0
0
0
12
0
0
0
56
0
0
23
12
% T
% Val:
12
12
0
0
12
0
0
0
0
0
0
0
0
0
78
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
67
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _