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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FADD All Species: 4.55
Human Site: T124 Identified Species: 11.11
UniProt: Q13158 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13158 NP_003815.1 208 23279 T124 R Q L K V S D T K I D S I E D
Chimpanzee Pan troglodytes XP_508611 208 23330 T124 R Q L K V S D T K I D S I E D
Rhesus Macaque Macaca mulatta XP_001100468 207 23078 A124 R Q L K V S D A K I D S I E D
Dog Lupus familis XP_854485 175 19520 A81 R Y L K V T D A K I D A I E E
Cat Felis silvestris
Mouse Mus musculus Q61160 205 22942 A124 R E L K V S E A K M D G I E E
Rat Rattus norvegicus NP_690920 208 23106 A124 R E L K V S E A K I D G I E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507113 190 22233 R96 T E D L L D P R E R E R L S A
Chicken Gallus gallus XP_421073 195 22801 V105 K E R R L Q K V V I E V I C E
Frog Xenopus laevis NP_001089017 188 21457 Q94 D S L A P G T Q E R D P L D D
Zebra Danio Brachydanio rerio XP_001923893 192 22093 V111 R I N T A T E V V V E Q L G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 93.7 48 N.A. 67.7 68.2 N.A. 44.2 43.2 37.5 35 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 95.6 60.5 N.A. 84.6 82.2 N.A. 64.4 63.4 58.1 56.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 66.6 N.A. 60 66.6 N.A. 0 13.3 20 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. 33.3 53.3 40 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 0 0 40 0 0 0 10 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 10 0 10 0 0 10 40 0 0 0 70 0 0 10 40 % D
% Glu: 0 40 0 0 0 0 30 0 20 0 30 0 0 60 40 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 0 20 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 60 0 0 70 0 0 % I
% Lys: 10 0 0 60 0 0 10 0 60 0 0 0 0 0 10 % K
% Leu: 0 0 70 10 20 0 0 0 0 0 0 0 30 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 10 0 0 0 0 10 0 0 0 % P
% Gln: 0 30 0 0 0 10 0 10 0 0 0 10 0 0 0 % Q
% Arg: 70 0 10 10 0 0 0 10 0 20 0 10 0 0 0 % R
% Ser: 0 10 0 0 0 50 0 0 0 0 0 30 0 10 0 % S
% Thr: 10 0 0 10 0 20 10 20 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 60 0 0 20 20 10 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _