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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRDX4 All Species: 22.73
Human Site: S140 Identified Species: 35.71
UniProt: Q13162 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13162 NP_006397.1 271 30540 S140 D R L E E F R S I N T E V V A
Chimpanzee Pan troglodytes XP_001144211 335 37352 R140 G D R L E K F R S I N T E V V
Rhesus Macaque Macaca mulatta XP_001087492 271 30482 S140 D R L E E F R S I N T E V V A
Dog Lupus familis XP_548896 272 30364 S141 D R I E E F K S I N T E V V A
Cat Felis silvestris
Mouse Mus musculus O08807 274 31034 S143 D R I E E F K S I N T E V V A
Rat Rattus norvegicus Q9Z0V5 273 30989 S142 D R I E E F K S I N T E V V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509414 221 24717 E94 E F R A I N T E V V A C S V D
Chicken Gallus gallus P0CB50 199 22296 E72 E F K K I N C E I I G A S V D
Frog Xenopus laevis NP_001088817 268 29936 S137 D R I E E F R S I N T E V V A
Zebra Danio Brachydanio rerio XP_002661980 260 29093 A129 D R V H E F Q A I N A E V V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3P0 194 21719 E67 E F R K I N C E V I G C S T D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q21824 226 24914 V99 F R S L G A E V V A C S C D S
Sea Urchin Strong. purpuratus XP_784460 248 27070 Q121 V A I S V D S Q F T H L A W I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C5R8 271 29543 K140 D R Y E E F E K L N T E V L G
Baker's Yeast Sacchar. cerevisiae P34760 196 21571 V69 F E E Q G A Q V L F A S T D S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.6 98.5 92.6 N.A. 89.4 88.6 N.A. 70.1 50.5 80.4 77.8 N.A. 49 N.A. 47.2 69.3
Protein Similarity: 100 78.2 99.2 95.5 N.A. 92.6 92.3 N.A. 76 61.2 85.2 85.9 N.A. 59.7 N.A. 60.8 78.2
P-Site Identity: 100 13.3 100 86.6 N.A. 86.6 86.6 N.A. 6.6 13.3 93.3 66.6 N.A. 0 N.A. 6.6 0
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. 20 26.6 100 86.6 N.A. 20 N.A. 20 6.6
Percent
Protein Identity: N.A. N.A. N.A. 44.2 41.3 N.A.
Protein Similarity: N.A. N.A. N.A. 60.8 52.7 N.A.
P-Site Identity: N.A. N.A. N.A. 60 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 0 14 0 7 0 7 20 7 7 0 47 % A
% Cys: 0 0 0 0 0 0 14 0 0 0 7 14 7 0 0 % C
% Asp: 54 7 0 0 0 7 0 0 0 0 0 0 0 14 20 % D
% Glu: 20 7 7 47 60 0 14 20 0 0 0 54 7 0 0 % E
% Phe: 14 20 0 0 0 54 7 0 7 7 0 0 0 0 0 % F
% Gly: 7 0 0 0 14 0 0 0 0 0 14 0 0 0 7 % G
% His: 0 0 0 7 0 0 0 0 0 0 7 0 0 0 0 % H
% Ile: 0 0 34 0 20 0 0 0 54 20 0 0 0 0 7 % I
% Lys: 0 0 7 14 0 7 20 7 0 0 0 0 0 0 0 % K
% Leu: 0 0 14 14 0 0 0 0 14 0 0 7 0 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 20 0 0 0 54 7 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 7 0 0 14 7 0 0 0 0 0 0 0 % Q
% Arg: 0 60 20 0 0 0 20 7 0 0 0 0 0 0 0 % R
% Ser: 0 0 7 7 0 0 7 40 7 0 0 14 20 0 14 % S
% Thr: 0 0 0 0 0 0 7 0 0 7 47 7 7 7 0 % T
% Val: 7 0 7 0 7 0 0 14 20 7 0 0 54 67 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _