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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRDX4 All Species: 36.97
Human Site: S185 Identified Species: 58.1
UniProt: Q13162 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13162 NP_006397.1 271 30540 S185 S D L T H Q I S K D Y G V Y L
Chimpanzee Pan troglodytes XP_001144211 335 37352 S186 S D L T H Q I S K D Y G V Y L
Rhesus Macaque Macaca mulatta XP_001087492 271 30482 S185 S D L T H Q I S K D Y G V Y L
Dog Lupus familis XP_548896 272 30364 S186 S D L T H Q I S K D Y G V Y L
Cat Felis silvestris
Mouse Mus musculus O08807 274 31034 S188 S D L N H Q I S K D Y G V Y L
Rat Rattus norvegicus Q9Z0V5 273 30989 S187 S D L N H Q I S K D Y G V Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509414 221 24717 Y138 T R Q I S K D Y G V Y L E D L
Chicken Gallus gallus P0CB50 199 22296 Y116 K R V I A K D Y G V L K E D E
Frog Xenopus laevis NP_001088817 268 29936 S182 S D L T H Q I S K D Y G V Y L
Zebra Danio Brachydanio rerio XP_002661980 260 29093 S174 S D L T H Q I S K D Y G V F L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3P0 194 21719 Y111 S M K V A R D Y G V L D E E T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q21824 226 24914 G143 K K I A D S F G V L D K E S G
Sea Urchin Strong. purpuratus XP_784460 248 27070 H165 V L L E D L G H T L R G L F I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C5R8 271 29543 S185 S D I T K S I S K S F G V L I
Baker's Yeast Sacchar. cerevisiae P34760 196 21571 G113 H S L S R D Y G V L I E E E G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.6 98.5 92.6 N.A. 89.4 88.6 N.A. 70.1 50.5 80.4 77.8 N.A. 49 N.A. 47.2 69.3
Protein Similarity: 100 78.2 99.2 95.5 N.A. 92.6 92.3 N.A. 76 61.2 85.2 85.9 N.A. 59.7 N.A. 60.8 78.2
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 13.3 0 100 93.3 N.A. 6.6 N.A. 0 13.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 26.6 13.3 100 100 N.A. 13.3 N.A. 6.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. 44.2 41.3 N.A.
Protein Similarity: N.A. N.A. N.A. 60.8 52.7 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 14 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 60 0 0 14 7 20 0 0 54 7 7 0 14 0 % D
% Glu: 0 0 0 7 0 0 0 0 0 0 0 7 34 14 7 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 7 0 0 14 0 % F
% Gly: 0 0 0 0 0 0 7 14 20 0 0 67 0 0 14 % G
% His: 7 0 0 0 54 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 0 14 14 0 0 60 0 0 0 7 0 0 0 14 % I
% Lys: 14 7 7 0 7 14 0 0 60 0 0 14 0 0 0 % K
% Leu: 0 7 67 0 0 7 0 0 0 20 14 7 7 7 60 % L
% Met: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 7 0 0 54 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 14 0 0 7 7 0 0 0 0 7 0 0 0 0 % R
% Ser: 67 7 0 7 7 14 0 60 0 7 0 0 0 7 0 % S
% Thr: 7 0 0 47 0 0 0 0 7 0 0 0 0 0 7 % T
% Val: 7 0 7 7 0 0 0 0 14 20 0 0 60 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 20 0 0 60 0 0 47 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _