KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRDX4
All Species:
36.97
Human Site:
S185
Identified Species:
58.1
UniProt:
Q13162
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13162
NP_006397.1
271
30540
S185
S
D
L
T
H
Q
I
S
K
D
Y
G
V
Y
L
Chimpanzee
Pan troglodytes
XP_001144211
335
37352
S186
S
D
L
T
H
Q
I
S
K
D
Y
G
V
Y
L
Rhesus Macaque
Macaca mulatta
XP_001087492
271
30482
S185
S
D
L
T
H
Q
I
S
K
D
Y
G
V
Y
L
Dog
Lupus familis
XP_548896
272
30364
S186
S
D
L
T
H
Q
I
S
K
D
Y
G
V
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
O08807
274
31034
S188
S
D
L
N
H
Q
I
S
K
D
Y
G
V
Y
L
Rat
Rattus norvegicus
Q9Z0V5
273
30989
S187
S
D
L
N
H
Q
I
S
K
D
Y
G
V
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509414
221
24717
Y138
T
R
Q
I
S
K
D
Y
G
V
Y
L
E
D
L
Chicken
Gallus gallus
P0CB50
199
22296
Y116
K
R
V
I
A
K
D
Y
G
V
L
K
E
D
E
Frog
Xenopus laevis
NP_001088817
268
29936
S182
S
D
L
T
H
Q
I
S
K
D
Y
G
V
Y
L
Zebra Danio
Brachydanio rerio
XP_002661980
260
29093
S174
S
D
L
T
H
Q
I
S
K
D
Y
G
V
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3P0
194
21719
Y111
S
M
K
V
A
R
D
Y
G
V
L
D
E
E
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21824
226
24914
G143
K
K
I
A
D
S
F
G
V
L
D
K
E
S
G
Sea Urchin
Strong. purpuratus
XP_784460
248
27070
H165
V
L
L
E
D
L
G
H
T
L
R
G
L
F
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5R8
271
29543
S185
S
D
I
T
K
S
I
S
K
S
F
G
V
L
I
Baker's Yeast
Sacchar. cerevisiae
P34760
196
21571
G113
H
S
L
S
R
D
Y
G
V
L
I
E
E
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.6
98.5
92.6
N.A.
89.4
88.6
N.A.
70.1
50.5
80.4
77.8
N.A.
49
N.A.
47.2
69.3
Protein Similarity:
100
78.2
99.2
95.5
N.A.
92.6
92.3
N.A.
76
61.2
85.2
85.9
N.A.
59.7
N.A.
60.8
78.2
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
13.3
0
100
93.3
N.A.
6.6
N.A.
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
26.6
13.3
100
100
N.A.
13.3
N.A.
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.2
41.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.8
52.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
14
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
60
0
0
14
7
20
0
0
54
7
7
0
14
0
% D
% Glu:
0
0
0
7
0
0
0
0
0
0
0
7
34
14
7
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
7
0
0
14
0
% F
% Gly:
0
0
0
0
0
0
7
14
20
0
0
67
0
0
14
% G
% His:
7
0
0
0
54
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
14
14
0
0
60
0
0
0
7
0
0
0
14
% I
% Lys:
14
7
7
0
7
14
0
0
60
0
0
14
0
0
0
% K
% Leu:
0
7
67
0
0
7
0
0
0
20
14
7
7
7
60
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
54
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
14
0
0
7
7
0
0
0
0
7
0
0
0
0
% R
% Ser:
67
7
0
7
7
14
0
60
0
7
0
0
0
7
0
% S
% Thr:
7
0
0
47
0
0
0
0
7
0
0
0
0
0
7
% T
% Val:
7
0
7
7
0
0
0
0
14
20
0
0
60
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
20
0
0
60
0
0
47
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _